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Catalog Number:
07051
CAS Number:
252049-14-2
Fmoc-4-tert-butyl-D-phenylalanine
Purity:
≥ 95% (HPLC)
Synonym(s):
Fmoc-D-Phe(4-tBu)-OH, Fmoc-p-tBu-D-Phe-OH
Documents
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Product Information

Fmoc-4-tert-butyl-D-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure, characterized by the tert-butyl group, enhances its solubility and stability, making it an ideal choice for researchers working in organic chemistry and biochemistry.

In practical applications, Fmoc-4-tert-butyl-D-phenylalanine is particularly valuable in the development of pharmaceuticals and biologically active peptides. Its ability to facilitate the formation of complex peptide chains allows for the creation of novel compounds with potential therapeutic effects. Researchers appreciate its compatibility with various coupling reagents and its efficiency in solid-phase peptide synthesis, which streamlines the production process. This compound stands out for its high purity and reliability, ensuring consistent results in laboratory settings.

Synonyms
Fmoc-D-Phe(4-tBu)-OH, Fmoc-p-tBu-D-Phe-OH
CAS Number
252049-14-2
Purity
≥ 95% (HPLC)
Molecular Formula
C28H29NO4
Molecular Weight
443.56
MDL Number
MFCD02094467
PubChem ID
50853302
Appearance
White solid
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-Phe(4-tBu)-OH, Fmoc-p-tBu-D-Phe-OH
CAS Number
252049-14-2
Purity
≥ 95% (HPLC)
Molecular Formula
C28H29NO4
Molecular Weight
443.56
MDL Number
MFCD02094467
PubChem ID
50853302
Appearance
White solid
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-4-tert-butyl-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound is a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide sequences with high purity.
  • Drug Development: It plays a significant role in the pharmaceutical industry for developing peptide-based drugs, offering a stable and effective way to modify peptide structures for enhanced biological activity.
  • Bioconjugation: The chemical is used in bioconjugation processes, where it helps attach peptides to other biomolecules, improving the efficacy of targeted drug delivery systems.
  • Research in Neuroscience: Researchers utilize this compound to study neuropeptides, which are crucial in understanding various neurological functions and disorders, potentially leading to new therapeutic approaches.
  • Protein Engineering: It is employed in protein engineering to modify amino acid sequences, enhancing the stability and functionality of proteins for various industrial applications.

Citations