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Catalog Number:
07031
CAS Number:
218962-77-7
4-tert-Butyloxycarbonyl-L-phenylalanine
Purity:
≥ 95% (HPLC)
Synonym(s):
L-Phe(4-COOtBu)-OH, p-(Carboxy-tert-butyl)-L-phenylalanine
Documents
$130.00 /100MG
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Product Information

4-tert-Butyloxycarbonyl-L-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids without interfering with other functional groups. Its unique tert-butoxycarbonyl (Boc) group provides stability during the synthesis process, making it an essential tool for chemists in the development of complex peptide structures.

In addition to its role in peptide synthesis, 4-tert-Butyloxycarbonyl-L-phenylalanine is also valuable in the production of biologically active compounds and drug candidates. Researchers appreciate its compatibility with various coupling reagents and its ability to enhance the solubility of peptides in organic solvents. This compound is particularly useful in the pharmaceutical industry for the design of targeted therapies and biologics, where precise control over molecular structure is crucial. Its application in the development of novel therapeutics highlights its significance in advancing drug discovery and development.

Synonyms
L-Phe(4-COOtBu)-OH, p-(Carboxy-tert-butyl)-L-phenylalanine
CAS Number
218962-77-7
Purity
≥ 95% (HPLC)
Molecular Formula
C14H19NO4
Molecular Weight
265.46
MDL Number
MFCD01318767
PubChem ID
18680396
Appearance
White powder
Conditions
Store at ≤ -15 °C
General Information
Synonyms
L-Phe(4-COOtBu)-OH, p-(Carboxy-tert-butyl)-L-phenylalanine
CAS Number
218962-77-7
Purity
≥ 95% (HPLC)
Molecular Formula
C14H19NO4
Molecular Weight
265.46
MDL Number
MFCD01318767
PubChem ID
18680396
Appearance
White powder
Conditions
Store at ≤ -15 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-tert-Butyloxycarbonyl-L-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for selective reactions without interfering with other functional groups. This is crucial in the pharmaceutical industry for developing new drugs.
  • Drug Development: It plays a significant role in the design of peptide-based therapeutics, particularly in cancer treatment, where modified peptides can enhance efficacy and reduce side effects.
  • Bioconjugation: The compound is used in bioconjugation processes, linking biomolecules like proteins and antibodies to therapeutic agents, improving targeting and delivery in drug formulations.
  • Research in Protein Engineering: It aids researchers in modifying amino acids in proteins, which can lead to the development of proteins with enhanced stability and activity for various applications in biotechnology.
  • Analytical Chemistry: This chemical is utilized in analytical methods to study protein interactions and structures, providing insights that are essential for understanding biological processes and developing new diagnostic tools.

Citations