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Catalog Number:
07018
CAS Number:
80102-27-8
Boc-4-methyl-D-phenylalanine
Purity:
≥ 99% (HPLC)
Synonym(s):
Boc-4-methyl-D-phenylalanine, Boc-p-Me-D-Phe-OH, (R-Boc-2-amino-3-(4-methylphenyl)propionic acid
Documents
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Product Information

Boc-4-methyl-D-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a protective Boc (tert-butyloxycarbonyl) group, which enhances its stability and solubility, making it an ideal choice for researchers working on complex peptide sequences. Its unique structure, characterized by a 4-methylphenyl side chain, allows for increased hydrophobic interactions, which can be beneficial in the design of bioactive peptides and drug candidates.

In the pharmaceutical industry, Boc-4-methyl-D-phenylalanine is particularly valuable in the development of peptide-based therapeutics, where it can serve as a building block for creating potent and selective inhibitors. Its application extends to the synthesis of cyclic peptides, which are known for their enhanced stability and bioavailability compared to linear peptides. Researchers appreciate its ease of incorporation into various peptide sequences, facilitating the exploration of structure-activity relationships in drug discovery. With its robust profile, Boc-4-methyl-D-phenylalanine stands out as a crucial component in advancing peptide chemistry and therapeutic development.

Synonyms
Boc-4-methyl-D-phenylalanine, Boc-p-Me-D-Phe-OH, (R-Boc-2-amino-3-(4-methylphenyl)propionic acid
CAS Number
80102-27-8
Purity
≥ 99% (HPLC)
Molecular Formula
C15H21NO4
Molecular Weight
279.34
MDL Number
MFCD01317726
PubChem ID
4350674
Melting Point
80-86 ?C
Appearance
White powder
Optical Rotation
[a]D20 = -32 ± 2º (C=1 in EtOAc)
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-4-methyl-D-phenylalanine, Boc-p-Me-D-Phe-OH, (R-Boc-2-amino-3-(4-methylphenyl)propionic acid
CAS Number
80102-27-8
Purity
≥ 99% (HPLC)
Molecular Formula
C15H21NO4
Molecular Weight
279.34
MDL Number
MFCD01317726
PubChem ID
4350674
Melting Point
80-86 ?C
Appearance
White powder
Optical Rotation
[a]D20 = -32 ± 2º (C=1 in EtOAc)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-4-methyl-D-phenylalanine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, especially in the development of therapeutic proteins and biologics.
  • Drug Development: It plays a crucial role in the design of new drugs, particularly those targeting specific receptors or enzymes, enhancing the efficacy of pharmaceutical formulations.
  • Biotechnology: Used in the production of modified amino acids, it aids in creating proteins with altered properties, beneficial for various biotechnological applications.
  • Research in Neuroscience: This compound is valuable in studying neurotransmitter systems, helping researchers understand the role of amino acids in brain function and behavior.
  • Analytical Chemistry: It is employed in chromatographic techniques for the separation and analysis of complex mixtures, providing insights into chemical composition and purity.

Citations