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Catalog Number:
06903
CAS Number:
201335-88-8
Fmoc-O-methyl-D-tyrosine
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Fmoc-D-Tyr(Me)-OH, Fmoc-p-methoxy-D-Phe-OH
Documents
$58.69 /1G
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Product Information

Fmoc-O-methyl-D-tyrosine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which provides stability during the synthesis process while allowing for selective deprotection. Its unique structure, characterized by the presence of a methoxy group on the aromatic ring, enhances its solubility and reactivity, making it an excellent choice for researchers focused on developing complex peptides and proteins.

In the pharmaceutical industry, Fmoc-O-methyl-D-tyrosine serves as a crucial building block for the synthesis of bioactive peptides, which can be used in therapeutic applications such as cancer treatment and hormone regulation. Its ability to facilitate the introduction of D-amino acids into peptide sequences allows for the creation of more stable and bioactive compounds. Researchers appreciate its compatibility with various coupling reagents and its effectiveness in solid-phase peptide synthesis, making it a preferred choice for both academic and industrial applications.

Synonyms
Fmoc-D-Tyr(Me)-OH, Fmoc-p-methoxy-D-Phe-OH
CAS Number
201335-88-8
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C25H23NO5
Molecular Weight
417.47
MDL Number
MFCD00237393
PubChem ID
6915697
Melting Point
158 - 165 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -7 ± 2 º (C=1 in EtOAc)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Tyr(Me)-OH, Fmoc-p-methoxy-D-Phe-OH
CAS Number
201335-88-8
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C25H23NO5
Molecular Weight
417.47
MDL Number
MFCD00237393
PubChem ID
6915697
Melting Point
158 - 165 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -7 ± 2 º (C=1 in EtOAc)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-methyl-D-tyrosine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, enabling researchers to create complex molecules for drug development and biological studies.
  • Drug Discovery: It plays a significant role in the pharmaceutical industry for developing new therapeutic agents, particularly in targeting specific receptors in the body.
  • Bioconjugation: Its unique structure allows for effective bioconjugation techniques, which are essential in creating targeted drug delivery systems and improving therapeutic efficacy.
  • Research in Neuroscience: The compound is used in studies related to neurotransmitter pathways, helping researchers understand the role of modified amino acids in brain function.
  • Protein Engineering: Fmoc-O-methyl-D-tyrosine is valuable in the field of protein engineering, where it aids in the design of proteins with enhanced stability and functionality.

Citations