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Catalog Number:
06804
Nα-Fmoc-L-tryptophan-2-chlorotrityl resin (0.3 - 0.8 meq/g, 200 - 400 mesh)
Synonym(s):
Fmoc-L-Trp-2-chlorotrityl resin
Documents
$30.00 /1G
Pack Size Availability Price
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Product Information

Na-Fmoc-L-tryptophan-2-chlorotrityl resin is a highly specialized resin used primarily in peptide synthesis and solid-phase peptide synthesis (SPPS). This resin is particularly valued for its ability to facilitate the efficient coupling of amino acids, enabling researchers to construct complex peptides with precision. The Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for easy deprotection under mild conditions, making it an ideal choice for sensitive sequences. Its chlorotrityl functionality enhances the stability and reactivity of the resin, ensuring high yields and purity of the final peptide products.

This resin is widely utilized in pharmaceutical research, particularly in the development of peptide-based therapeutics and vaccines. Its unique properties make it suitable for synthesizing a variety of biologically active peptides, including those used in drug discovery and development. Researchers appreciate its compatibility with automated synthesizers, which streamlines the synthesis process and reduces labor costs. Overall, Na-Fmoc-L-tryptophan-2-chlorotrityl resin stands out for its efficiency and effectiveness in peptide synthesis, making it a valuable asset in both academic and industrial laboratories.

Synonyms
Fmoc-L-Trp-2-chlorotrityl resin
Molecular Weight
0
MDL Number
MFCD03792296
Appearance
Pale yellow to light brown beads
Substitution
0.3 - 0.8 meq/g
Mesh Size
200 - 400 mesh
Conditions
Store at 0-8 °C
%DVB
1% DVB
General Information
Synonyms
Fmoc-L-Trp-2-chlorotrityl resin
Molecular Weight
0
MDL Number
MFCD03792296
Appearance
Pale yellow to light brown beads
Substitution
0.3 - 0.8 meq/g
Mesh Size
200 - 400 mesh
Conditions
Store at 0-8 °C
%DVB
1% DVB
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-L-tryptophan-2-chlorotrityl resin is widely utilized in research focused on

  • Peptide Synthesis: This resin is primarily used in solid-phase peptide synthesis, allowing researchers to create complex peptides efficiently. Its ability to anchor amino acids makes it a preferred choice for synthesizing custom peptides for various applications.
  • Drug Development: In pharmaceutical research, this resin aids in the development of peptide-based drugs. Its compatibility with automated synthesizers streamlines the process of producing therapeutic peptides, which can lead to quicker drug discovery.
  • Biotechnology: The resin is valuable in the biotechnology sector for producing peptides that can be used in diagnostics or as research tools. Its high purity and yield are crucial for obtaining reliable results in experiments.
  • Research in Neuroscience: Given that tryptophan is a precursor to serotonin, this resin is used to synthesize peptides that can help study neurotransmitter functions, contributing to advancements in understanding mood disorders.
  • Custom Peptide Libraries: Researchers utilize this resin to create diverse peptide libraries for screening purposes. This application is essential in identifying new drug candidates or understanding protein interactions.

Citations