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Catalog Number:
06803
Fmoc-O-tert-butyl-L-threonine 2-chlorotrityl resin (0.3 - 0.9 meq/g, 200 - 400 mesh)
Synonym(s):
Fmoc-L-Thr(tBu)-2-chlorotrityl resin
Documents
$36.65 /1G
Pack Size Availability Price
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Product Information

Fmoc-O-tert-butyl-L-threonine 2-chlorotrityl resin is a specialized resin used extensively in peptide synthesis and solid-phase peptide synthesis (SPPS). This resin is particularly valued for its ability to facilitate the efficient assembly of peptides, providing a stable and easily cleavable protecting group for the amino acid threonine. Its unique structure allows for high loading capacity and excellent compatibility with various coupling reagents, making it an ideal choice for researchers and professionals in the fields of biochemistry and pharmaceutical development.

The resin's robust nature ensures that it can withstand the rigorous conditions of peptide synthesis, while its chlorotrityl functionality allows for selective cleavage under mild conditions, preserving the integrity of the synthesized peptides. This makes it particularly advantageous for the production of complex peptides and therapeutic proteins. Researchers can leverage this resin to streamline their workflows, enhance yield, and improve the purity of their final products, ultimately accelerating the development of new therapeutics and research applications.

Synonyms
Fmoc-L-Thr(tBu)-2-chlorotrityl resin
MDL Number
MFCD03792294
Appearance
Light yellowish orange beads
Substitution
0.3 - 0.9 meq/g
Mesh Size
200 - 400 mesh
Conditions
Store at 0-8 °C
%DVB
1% DVB
General Information
Synonyms
Fmoc-L-Thr(tBu)-2-chlorotrityl resin
MDL Number
MFCD03792294
Appearance
Light yellowish orange beads
Substitution
0.3 - 0.9 meq/g
Mesh Size
200 - 400 mesh
Conditions
Store at 0-8 °C
%DVB
1% DVB
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-tert-butyl-L-threonine 2-chlorotrityl resin is widely utilized in research focused on:

  • Peptide Synthesis: This resin is essential for solid-phase peptide synthesis, allowing researchers to efficiently create peptides with high purity and yield.
  • Drug Development: Its application in synthesizing peptide-based drugs enables the development of therapeutics that target specific biological pathways, enhancing treatment efficacy.
  • Bioconjugation: The resin facilitates the attachment of peptides to other biomolecules, aiding in the creation of conjugates for targeted drug delivery systems.
  • Protein Engineering: By incorporating this resin in the synthesis process, researchers can modify protein structures, leading to innovations in enzyme design and function.
  • Research in Immunology: It is used to produce peptide antigens for vaccine development, contributing to advancements in immunotherapy and disease prevention.

Citations