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Catalog Number:
06746
CAS Number:
212651-48-4
Fmoc-Gly-Pro-OH
Purity:
≥ 95% (HPLC)
Synonym(s):
Fmoc-gycyl-L-proline
Documents
$75.00 /250MG
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Product Information

Fmoc-Gly-Pro-OH is a valuable building block in peptide synthesis, particularly favored for its role in solid-phase peptide synthesis (SPPS). This compound, also known as Fmoc-glycine proline hydroxyl, features a fluorenylmethoxycarbonyl (Fmoc) protecting group that allows for selective deprotection during synthesis, making it an essential tool for researchers and industry professionals in the field of biochemistry and pharmaceuticals. Its unique structure enhances stability and solubility, facilitating the formation of complex peptides and proteins.

This compound is particularly useful in the development of therapeutic peptides and proteins, enabling the creation of bioactive molecules with specific functionalities. Researchers have successfully utilized Fmoc-Gly-Pro-OH in the synthesis of peptide-based drugs and in studies related to protein folding and interactions. Its ability to provide a stable backbone while allowing for functional group modifications makes it a preferred choice for those looking to innovate in peptide design and development. With its proven track record in various applications, Fmoc-Gly-Pro-OH stands out as a reliable and efficient reagent for advancing peptide chemistry.

Synonyms
Fmoc-gycyl-L-proline
CAS Number
212651-48-4
Purity
≥ 95% (HPLC)
Molecular Formula
C22H22N2O5
Molecular Weight
394.43
MDL Number
MFCD00190883
PubChem ID
21303826
Melting Point
108 - 124 ?C (Lit.)
Appearance
White solid
Optical Rotation
[a]D20 = -48 ± 3 º (C=1 in 80% Acetone) (Lit.)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-gycyl-L-proline
CAS Number
212651-48-4
Purity
≥ 95% (HPLC)
Molecular Formula
C22H22N2O5
Molecular Weight
394.43
MDL Number
MFCD00190883
PubChem ID
21303826
Melting Point
108 - 124 ?C (Lit.)
Appearance
White solid
Optical Rotation
[a]D20 = -48 ± 3 º (C=1 in 80% Acetone) (Lit.)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-Gly-Pro-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound is a key building block in the synthesis of peptides, especially in solid-phase peptide synthesis, allowing for the efficient assembly of complex peptide chains.
  • Drug Development: In pharmaceutical research, it aids in the development of peptide-based drugs, providing a stable structure that enhances bioavailability and efficacy.
  • Bioconjugation: It is used in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, improving the functionality of diagnostic tools and therapeutic agents.
  • Protein Engineering: Researchers leverage its properties to design and modify proteins, facilitating studies on protein interactions and functions, which are crucial in biotechnology.
  • Research in Neuroscience: The compound is applied in studies related to neuropeptides, helping scientists understand signaling pathways and potential treatments for neurological disorders.

Citations