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Catalog Number:
06705
CAS Number:
69568-63-4
Boc-L-threonine hydrazide
Purity:
≥ 97% (HPLC)
Synonym(s):
Boc-L-Thr-NHNH2
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Product Information

Boc-L-threonine hydrazide is a versatile compound widely utilized in peptide synthesis and drug development. This hydrazide derivative of threonine features a tert-butyl carbamate protecting group, which enhances its stability and reactivity in various chemical reactions. Its unique structure allows for the selective modification of peptides, making it an essential building block in the design of bioactive molecules. Researchers in the pharmaceutical industry often leverage Boc-L-threonine hydrazide for the synthesis of peptide-based therapeutics, particularly in the development of inhibitors and enzyme substrates.

The compound's ability to facilitate the introduction of hydrazine functionalities into peptides opens up new avenues for creating innovative drug candidates with improved efficacy and selectivity. Additionally, its favorable solubility and compatibility with standard coupling reagents make it an attractive choice for chemists looking to streamline their synthetic processes. With its significant role in advancing peptide chemistry, Boc-L-threonine hydrazide stands out as a valuable tool for researchers aiming to explore the frontiers of medicinal chemistry.

Synonyms
Boc-L-Thr-NHNH2
CAS Number
69568-63-4
Purity
≥ 97% (HPLC)
Molecular Formula
C9H19N3O4
Molecular Weight
233.34
MDL Number
MFCD00190834
PubChem ID
91979660
Melting Point
141-147 ?C
Optical Rotation
[a]D20 = -7 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-L-Thr-NHNH2
CAS Number
69568-63-4
Purity
≥ 97% (HPLC)
Molecular Formula
C9H19N3O4
Molecular Weight
233.34
MDL Number
MFCD00190834
PubChem ID
91979660
Melting Point
141-147 ?C
Optical Rotation
[a]D20 = -7 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-threonine hydrazide is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a building block in the synthesis of peptides, particularly in the development of therapeutic proteins and vaccines, enhancing the efficiency of the process.
  • Drug Development: It plays a crucial role in the pharmaceutical industry for creating hydrazone derivatives, which are important in designing new drug candidates with improved efficacy.
  • Bioconjugation: Boc-L-threonine hydrazide is used in bioconjugation techniques to attach biomolecules to surfaces or other molecules, facilitating targeted drug delivery systems.
  • Research in Enzyme Inhibition: This compound is valuable in studying enzyme inhibition mechanisms, helping researchers to understand and develop inhibitors for various diseases.
  • Protein Modification: It is employed in modifying proteins to study their structure and function, providing insights into protein interactions and stability.

Citations