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Catalog Number:
06640
CAS Number:
71989-25-8
L-Leucine 4-nitrophenyl ester hydrochloride
Purity:
≥ 98% (HPLC)
Synonym(s):
L-Leu-ONp·HCl, (S)-2-Amino-4-methyl-pentanoic acid 4-nitrophenyl ester
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Product Information

L-Leucine 4-nitrophenyl ester hydrochloride is a valuable compound in biochemical research and pharmaceutical applications. This derivative of the essential amino acid L-Leucine is recognized for its role in protein synthesis and metabolic regulation. Its unique structure enhances its solubility and bioavailability, making it an excellent choice for studies involving peptide synthesis and enzyme activity. Researchers often utilize this compound in the development of novel therapeutic agents, particularly in the fields of cancer research and metabolic disorders, where understanding amino acid interactions is crucial.

The compound's properties allow for its application in various assays and experimental setups, providing insights into protein interactions and cellular processes. Its ability to act as a substrate in enzymatic reactions makes it particularly useful for researchers exploring enzyme kinetics and mechanisms. Additionally, L-Leucine 4-nitrophenyl ester hydrochloride can serve as a building block in the synthesis of more complex molecules, offering significant advantages over similar compounds due to its stability and reactivity profile.

Synonyms
L-Leu-ONp·HCl, (S)-2-Amino-4-methyl-pentanoic acid 4-nitrophenyl ester
CAS Number
71989-25-8
Purity
≥ 98% (HPLC)
Molecular Formula
C12H16N2O4·HCl
Molecular Weight
288.68
MDL Number
MFCD00270558
PubChem ID
85978927
Melting Point
> 176 °C (dec.)
Appearance
Off-white powder
Optical Rotation
[α]D25 = +24 ± 1º (C=1 in 1N HCl)
Conditions
Store at 0-8 °C
General Information
Synonyms
L-Leu-ONp·HCl, (S)-2-Amino-4-methyl-pentanoic acid 4-nitrophenyl ester
CAS Number
71989-25-8
Purity
≥ 98% (HPLC)
Molecular Formula
C12H16N2O4·HCl
Molecular Weight
288.68
MDL Number
MFCD00270558
PubChem ID
85978927
Melting Point
> 176 °C (dec.)
Appearance
Off-white powder
Optical Rotation
[α]D25 = +24 ± 1º (C=1 in 1N HCl)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

L-Leucine 4-nitrophenyl ester hydrochloride is widely utilized in research focused on:

  • Biochemical Research: This compound serves as a substrate in enzyme assays, helping researchers study enzyme kinetics and mechanisms, particularly in protease activity.
  • Peptide Synthesis: It is used in the synthesis of peptides, allowing for the incorporation of L-leucine in various sequences, which is crucial for developing biologically active compounds.
  • Drug Development: The ester form enhances solubility and bioavailability of L-leucine, making it a valuable candidate in formulating new pharmaceuticals aimed at muscle recovery and metabolic health.
  • Analytical Chemistry: This compound is employed in chromatographic techniques for the separation and identification of amino acids, providing a reliable method for quality control in food and pharmaceutical industries.
  • Nutrition Science: It is investigated for its role in protein synthesis and muscle growth, offering insights into dietary supplements that can enhance athletic performance and recovery.

Citations