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Catalog Number:
06620
CAS Number:
63126-47-6
O-Methyl-L-prolinol
Purity:
≥ 99% (Chiral purity)
Synonym(s):
L-Prolinol methyl ether, (S-2-Methoxymethyl-pyrrolidine
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Product Information

O-Methyl-L-prolinol is a versatile chiral building block widely utilized in the synthesis of pharmaceuticals and agrochemicals. This compound, characterized by its unique pyrrolidine structure, offers significant advantages in asymmetric synthesis, making it an essential tool for researchers in medicinal chemistry. Its ability to act as a chiral auxiliary enhances the efficiency of enantioselective reactions, which is crucial in the development of active pharmaceutical ingredients (APIs).

In addition to its applications in drug synthesis, O-Methyl-L-prolinol serves as a valuable intermediate in the production of various bioactive compounds. Its methoxy group contributes to its reactivity, allowing for diverse functionalization opportunities. Researchers and industry professionals can leverage this compound to streamline their synthetic pathways, reduce waste, and improve overall yields. With its growing importance in the field of organic synthesis, O-Methyl-L-prolinol stands out as a key player in advancing chemical research and development.

Synonyms
L-Prolinol methyl ether, (S-2-Methoxymethyl-pyrrolidine
CAS Number
63126-47-6
Purity
≥ 99% (Chiral purity)
Molecular Formula
C6H13NO
Molecular Weight
115.14
MDL Number
MFCD00010408
PubChem ID
143953
Appearance
Colorless liquid
Optical Rotation
[a]20D = 2 ± 1 ° (C=2.01 in CH3OH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
L-Prolinol methyl ether, (S-2-Methoxymethyl-pyrrolidine
CAS Number
63126-47-6
Purity
≥ 99% (Chiral purity)
Molecular Formula
C6H13NO
Molecular Weight
115.14
MDL Number
MFCD00010408
PubChem ID
143953
Appearance
Colorless liquid
Optical Rotation
[a]20D = 2 ± 1 ° (C=2.01 in CH3OH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

O-Methyl-L-prolinol is widely utilized in research focused on:

  • Synthesis of Pharmaceuticals: This compound serves as a valuable intermediate in the synthesis of various pharmaceutical agents, particularly in the development of drugs targeting neurological disorders.
  • Chiral Auxiliary in Organic Reactions: It acts as a chiral auxiliary, enhancing the selectivity of reactions in asymmetric synthesis, which is crucial for producing enantiomerically pure compounds.
  • Biocatalysis: O-Methyl-L-prolinol is employed in biocatalytic processes, aiding in the production of fine chemicals and bioactive compounds with improved efficiency and lower environmental impact.
  • Research in Material Science: Its unique properties make it suitable for developing new materials, including polymers and coatings, that require specific functional characteristics.
  • Analytical Chemistry: This compound is used as a standard in analytical methods, helping researchers accurately quantify and analyze other compounds in complex mixtures.

Citations