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Catalog Number:
06427
CAS Number:
200259-87-6
Nα-Z-Nγ-trityl-D-asparagine
Purity:
≥ 98% (HPLC)
Synonym(s):
Z-D-Asn(Trt)-OH
Documents
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Product Information

Na-Z-Ng-trityl-D-asparagine is a versatile amino acid derivative that plays a crucial role in peptide synthesis and bioconjugation applications. This compound is particularly valued in the fields of medicinal chemistry and biotechnology due to its unique trityl protection, which enhances stability and solubility in various solvents. Researchers utilize Na-Z-Ng-trityl-D-asparagine for the development of peptide-based therapeutics, where its ability to facilitate selective reactions is essential. Its structural features allow for easy incorporation into complex peptide sequences, making it an ideal choice for those working on drug design and protein engineering.

In addition to its applications in peptide synthesis, Na-Z-Ng-trityl-D-asparagine is also used in the study of enzyme mechanisms and protein interactions. The compound's stability under physiological conditions makes it suitable for in vitro studies, providing insights into the behavior of peptides in biological systems. With its favorable properties, Na-Z-Ng-trityl-D-asparagine stands out as a valuable tool for researchers aiming to innovate in the fields of pharmaceuticals and biotechnology.

Synonyms
Z-D-Asn(Trt)-OH
CAS Number
200259-87-6
Purity
≥ 98% (HPLC)
Molecular Formula
C31H28N2O5
Molecular Weight
508.6
MDL Number
MFCD00237334
PubChem ID
53394877
Melting Point
184-191 ºC
Appearance
White to off-white powder
Optical Rotation
[a]D20 = +22 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Z-D-Asn(Trt)-OH
CAS Number
200259-87-6
Purity
≥ 98% (HPLC)
Molecular Formula
C31H28N2O5
Molecular Weight
508.6
MDL Number
MFCD00237334
PubChem ID
53394877
Melting Point
184-191 ºC
Appearance
White to off-white powder
Optical Rotation
[a]D20 = +22 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Z-Ng-trityl-D-asparagine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of biologically active molecules. Its unique structure allows for the incorporation of D-asparagine into peptide chains, enhancing their stability and activity.
  • Drug Development: In pharmaceutical research, it is used to create novel drug candidates. The ability to modify the amino acid sequence can lead to improved efficacy and reduced side effects in therapeutic agents.
  • Biotechnology: This chemical plays a crucial role in the production of recombinant proteins. By optimizing the amino acid composition, researchers can enhance protein yield and functionality, which is vital for vaccine development and enzyme production.
  • Research on Neurotransmitters: It is involved in studies related to neurotransmitter function, particularly in understanding the role of D-asparagine in the central nervous system. This research can lead to insights into neurological disorders and potential treatments.
  • Analytical Chemistry: The compound is also used as a standard in analytical methods for quantifying amino acids in various samples. Its distinct properties make it an ideal reference for ensuring accuracy in experimental results.

Citations