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Catalog Number:
06191
CAS Number:
53934-78-4
L-Phenylglycine tert-butyl ester
Purity:
≥ 99% (HPLC)
Synonym(s):
L-Phg-OtBu, H-Phg-OtBu
Documents
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Product Information

L-Phenylglycine tert-butyl ester is a versatile compound widely utilized in the synthesis of pharmaceuticals and agrochemicals. This compound, also known as tert-butyl (2S)-2-amino-2-phenylacetate, features a tert-butyl group that enhances its solubility and stability, making it an ideal choice for various chemical reactions. Its unique structure allows for the efficient production of amino acids and peptides, which are crucial in drug development and biochemistry. Researchers appreciate its role in asymmetric synthesis, where it serves as a chiral building block, facilitating the creation of enantiomerically pure compounds that are essential in the pharmaceutical industry.

In addition to its applications in drug synthesis, L-Phenylglycine tert-butyl ester is also valuable in the development of agrochemicals, where it contributes to the formulation of herbicides and pesticides. Its favorable properties, such as low toxicity and high reactivity, make it an attractive option for formulators seeking effective and environmentally friendly solutions. With its broad range of applications and benefits, this compound is a key ingredient for professionals looking to innovate in chemical synthesis and product development.

Synonyms
L-Phg-OtBu, H-Phg-OtBu
CAS Number
53934-78-4
Purity
≥ 99% (HPLC)
Molecular Formula
C12H17NO2
Molecular Weight
207.27
MDL Number
MFCD00238136
PubChem ID
12162441
Melting Point
178-189 ?C
Appearance
White powder
Optical Rotation
[a]D20 = +64.0 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
L-Phg-OtBu, H-Phg-OtBu
CAS Number
53934-78-4
Purity
≥ 99% (HPLC)
Molecular Formula
C12H17NO2
Molecular Weight
207.27
MDL Number
MFCD00238136
PubChem ID
12162441
Melting Point
178-189 ?C
Appearance
White powder
Optical Rotation
[a]D20 = +64.0 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

L-Phenylglycine tert-butyl ester is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as an important intermediate in the synthesis of various pharmaceuticals, particularly in the creation of amino acid derivatives that are crucial for drug formulation.
  • Peptide Synthesis: It is commonly used in solid-phase peptide synthesis, enhancing the efficiency and yield of peptide chains, which are essential in therapeutic applications.
  • Chiral Catalysis: The compound plays a significant role in asymmetric synthesis, acting as a chiral auxiliary that improves the selectivity of reactions, which is vital in producing enantiomerically pure compounds.
  • Research in Biochemistry: It is utilized in studies involving enzyme mechanisms and protein interactions, helping researchers understand biological processes at the molecular level.
  • Material Science: The compound is explored in the development of new materials, particularly in creating polymers with specific properties for use in various industrial applications.

Citations