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Catalog Number:
06076
CAS Number:
304698-96-2
Nim-Trityl-L-histidine tert-butyl ester hydrochloride
Purity:
≥ 96% (NMR)
Synonym(s):
H-His(t-Trt)-OtBu·HCl, H-His(1-Trt)-OtBu·HCl
Documents
$113.87 /250MG
Pack Size Availability Price
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Product Information

Nim-Trityl-L-histidine tert-butyl ester hydrochloride is a specialized compound that serves as a valuable building block in peptide synthesis and medicinal chemistry. This compound is recognized for its unique trityl protection, which enhances the stability and solubility of histidine residues during chemical reactions. Its tert-butyl ester functionality allows for selective deprotection under mild conditions, making it an ideal choice for researchers focused on developing peptide-based therapeutics.

In the pharmaceutical industry, Nim-Trityl-L-histidine tert-butyl ester hydrochloride is particularly useful in the design of bioactive peptides and drug candidates, where the integrity of the histidine side chain is crucial for biological activity. Its application extends to various fields, including drug discovery and development, where it aids in the synthesis of compounds with potential therapeutic effects. By utilizing this compound, researchers can streamline their synthesis processes while ensuring high yields and purity, ultimately accelerating the path to innovative drug solutions.

Synonyms
H-His(t-Trt)-OtBu·HCl, H-His(1-Trt)-OtBu·HCl
CAS Number
304698-96-2
Purity
≥ 96% (NMR)
Molecular Formula
C29H31N3O2·HCl
Molecular Weight
490.08
MDL Number
MFCD00798683
PubChem ID
72817345
Appearance
White powder
Conditions
Store at 0-8 °C
General Information
Synonyms
H-His(t-Trt)-OtBu·HCl, H-His(1-Trt)-OtBu·HCl
CAS Number
304698-96-2
Purity
≥ 96% (NMR)
Molecular Formula
C29H31N3O2·HCl
Molecular Weight
490.08
MDL Number
MFCD00798683
PubChem ID
72817345
Appearance
White powder
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Nim-Trityl-L-histidine tert-butyl ester hydrochloride is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids without disrupting the overall structure.
  • Drug Development: It plays a crucial role in the development of new pharmaceuticals, particularly in the design of histidine-containing compounds that can enhance drug efficacy.
  • Biochemical Research: Researchers use it to study protein interactions and enzyme activities, providing insights into biochemical pathways and mechanisms.
  • Analytical Chemistry: This compound is used as a standard in various analytical techniques, helping to ensure accuracy and reliability in quantitative analysis.
  • Therapeutic Applications: Its derivatives are being explored for potential therapeutic uses, particularly in areas such as cancer treatment and immunotherapy.

Citations