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Catalog Number:
06000
CAS Number:
90071-62-8
D-Proline tert-butyl ester
Purity:
≥ 99% (HPLC)
Synonym(s):
D-Pro-OtBu (syrup), (R-Pyrrolidine-2-carboxylic acid tert-butylester
Documents
$113.87 /1G
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Product Information

D-Proline tert-butyl ester is a versatile compound widely utilized in the synthesis of peptides and pharmaceuticals. This compound, known for its stability and ease of handling, serves as a valuable building block in organic synthesis, particularly in the development of proline derivatives. Its unique structure allows for enhanced solubility and reactivity, making it an ideal choice for researchers focused on drug development and peptide synthesis. The tert-butyl ester group not only improves the compound's stability but also facilitates easier purification processes, which is crucial in laboratory settings.

In addition to its applications in peptide synthesis, D-Proline tert-butyl ester is also employed in the production of various bioactive molecules, contributing to advancements in medicinal chemistry. Its ability to act as a chiral auxiliary further enhances its utility in asymmetric synthesis, allowing for the creation of compounds with specific stereochemistry. This compound stands out in comparison to similar esters due to its favorable properties, making it a preferred choice for professionals seeking reliable and effective reagents in their research and development projects.

Synonyms
D-Pro-OtBu (syrup), (R-Pyrrolidine-2-carboxylic acid tert-butylester
CAS Number
90071-62-8
Purity
≥ 99% (HPLC)
Molecular Formula
C9H17NO2
Molecular Weight
171.2
MDL Number
MFCD00083683
PubChem ID
102884
Appearance
Colorless liquid
Optical Rotation
[a]20D = 44 ± 1 º (C=1 in EtOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
D-Pro-OtBu (syrup), (R-Pyrrolidine-2-carboxylic acid tert-butylester
CAS Number
90071-62-8
Purity
≥ 99% (HPLC)
Molecular Formula
C9H17NO2
Molecular Weight
171.2
MDL Number
MFCD00083683
PubChem ID
102884
Appearance
Colorless liquid
Optical Rotation
[a]20D = 44 ± 1 º (C=1 in EtOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

D-Proline tert-butyl ester is widely utilized in research focused on:

  • Synthesis of Peptides: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of pharmaceuticals and biologically active compounds.
  • Chiral Auxiliary in Asymmetric Synthesis: It is employed as a chiral auxiliary, aiding in the production of enantiomerically pure compounds, which is crucial in drug development to ensure efficacy and safety.
  • Research in Protein Folding: The compound is used in studies related to protein folding and stability, helping researchers understand the mechanisms that affect protein behavior and function.
  • Development of Drug Formulations: Its properties make it suitable for formulating drugs, enhancing solubility and bioavailability, which are essential for effective therapeutic outcomes.
  • Applications in Material Science: D-Proline tert-butyl ester is also explored in material science for developing new polymers and materials with specific properties, benefiting industries like packaging and coatings.

Citations