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Catalog Number:
05998
CAS Number:
23235-03-2
D-Propargylglycine
Purity:
≥ 98%
Synonym(s):
D-Propargyl-Gly-OH, D-Pra-OH, H-D-Pra-OH
Documents
$65.40 /250MG
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Product Information

D-Propargylglycine is a versatile amino acid derivative known for its unique properties and applications in various fields, particularly in biochemical research and pharmaceutical development. This compound, also recognized as 2-aminopent-4-ynoic acid, serves as a potent inhibitor of the enzyme cystathionine gamma-lyase, which plays a crucial role in the metabolism of sulfur-containing amino acids. Its ability to modulate hydrogen sulfide production makes D-Propargylglycine an invaluable tool in studies related to cardiovascular health, neuroprotection, and cellular signaling pathways. Researchers have utilized this compound to explore its potential in treating conditions such as hypertension and neurodegenerative diseases, highlighting its significance in advancing therapeutic strategies.

In addition to its research applications, D-Propargylglycine's unique structure allows for potential use in the synthesis of novel compounds, making it a valuable asset in medicinal chemistry. Its compatibility with various chemical reactions opens avenues for developing new pharmaceuticals with enhanced efficacy and safety profiles. With its growing relevance in both academic and industrial settings, D-Propargylglycine stands out as a compound that not only supports innovative research but also contributes to the development of future therapeutic agents.

Synonyms
D-Propargyl-Gly-OH, D-Pra-OH, H-D-Pra-OH
CAS Number
23235-03-2
Purity
≥ 98%
Molecular Formula
C5H7NO2
Molecular Weight
113.1
MDL Number
MFCD00237407
PubChem ID
95575
Appearance
White powder
Conditions
Store at 0-8°C
General Information
Synonyms
D-Propargyl-Gly-OH, D-Pra-OH, H-D-Pra-OH
CAS Number
23235-03-2
Purity
≥ 98%
Molecular Formula
C5H7NO2
Molecular Weight
113.1
MDL Number
MFCD00237407
PubChem ID
95575
Appearance
White powder
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

D-Propargylglycine is widely utilized in research focused on:

  • Neuropharmacology: This compound acts as an inhibitor of the enzyme cystathionine γ-lyase, which is involved in the production of hydrogen sulfide, a signaling molecule in the brain. Its application helps in studying neurodegenerative diseases and potential therapies.
  • Metabolic Studies: Researchers use D-Propargylglycine to investigate metabolic pathways involving sulfur-containing amino acids. This aids in understanding metabolic disorders and developing nutritional interventions.
  • Cardiovascular Research: The compound's role in modulating hydrogen sulfide levels makes it valuable for studying cardiovascular health, particularly in conditions like hypertension and heart failure.
  • Pharmaceutical Development: D-Propargylglycine serves as a lead compound in the synthesis of new drugs targeting various diseases, providing a scaffold for the development of novel therapeutic agents.
  • Biochemical Assays: It is commonly used in laboratory assays to measure enzyme activity related to sulfur metabolism, offering insights into various biochemical processes and disease mechanisms.

Citations