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Catalog Number:
05971
CAS Number:
199119-46-5
Nim-Trityl-D-histidine
Purity:
≥ 99% (HPLC)
Synonym(s):
D-His(Trt)-OH
Documents
$139.11 /1G
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Product Information

Nim-Trityl-D-histidine is a specialized amino acid derivative that plays a crucial role in biochemical research and pharmaceutical applications. This compound features a unique trityl group that enhances its stability and solubility, making it an excellent choice for peptide synthesis and drug formulation. Researchers often utilize Nim-Trityl-D-histidine in the development of targeted therapies, particularly in the fields of oncology and neurology, where precise molecular interactions are essential. Its ability to act as a building block for more complex molecules allows for the creation of innovative therapeutics with improved efficacy and reduced side effects.

In addition to its applications in drug development, Nim-Trityl-D-histidine is also valuable in the study of protein interactions and enzyme activity. Its distinctive structure enables scientists to explore the dynamics of histidine residues in proteins, providing insights into enzyme catalysis and protein folding. This compound's versatility and effectiveness make it a preferred choice for researchers looking to advance their work in medicinal chemistry and biochemistry.

Synonyms
D-His(Trt)-OH
CAS Number
199119-46-5
Purity
≥ 99% (HPLC)
Molecular Formula
C25H23N3O2
Molecular Weight
397.48
MDL Number
MFCD00237099
PubChem ID
4198340
Melting Point
218-223 °C
Appearance
White to off-white powder
Optical Rotation
[α]D20 = -25 ± 2º (C=1 in AcOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
D-His(Trt)-OH
CAS Number
199119-46-5
Purity
≥ 99% (HPLC)
Molecular Formula
C25H23N3O2
Molecular Weight
397.48
MDL Number
MFCD00237099
PubChem ID
4198340
Melting Point
218-223 °C
Appearance
White to off-white powder
Optical Rotation
[α]D20 = -25 ± 2º (C=1 in AcOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Nim-Trityl-D-histidine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of therapeutic agents targeting various diseases.
  • Drug Development: Its unique structure allows researchers to explore new drug candidates, especially in the field of oncology, by modifying its properties to enhance efficacy and reduce side effects.
  • Bioconjugation: Nim-Trityl-D-histidine can be used in bioconjugation processes, linking drugs to antibodies for targeted therapy, improving the precision of treatments in cancer and autoimmune diseases.
  • Research in Enzyme Inhibition: This chemical is instrumental in studying enzyme interactions, providing insights into mechanisms of action that can lead to the development of novel inhibitors.
  • Diagnostic Applications: Its properties make it suitable for use in diagnostic assays, aiding in the detection of specific biomarkers in various medical conditions.

Citations