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Catalog Number:
05767
CAS Number:
119767-84-9
Fmoc-O-tert-butyl-L-threonine 3,4-dihydro-3-hydroxy-4-oxo-1,2,3-benzotriazine ester
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-Thr(tBu)-ODhbt
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Product Information

Fmoc-O-tert-butyl-L-threonine 3,4-dihydro-3-hydroxy-4-oxo-1,2,3-benzotriazine ester is a versatile compound widely utilized in peptide synthesis and drug development. This compound features a unique structure that combines the protective Fmoc (9-fluorenylmethyloxycarbonyl) group with a tert-butyl ether, making it an excellent choice for researchers looking to enhance the stability and solubility of peptides during synthesis. Its application extends to the creation of complex peptide sequences, where the Fmoc group allows for easy removal under mild conditions, facilitating the assembly of intricate molecular architectures.

In addition to its role in peptide synthesis, this compound is also valuable in medicinal chemistry, particularly in the design of bioactive molecules. The benzotriazine moiety contributes to its potential as a scaffold for drug discovery, offering opportunities for the development of novel therapeutics. Researchers can leverage its unique properties to explore new avenues in drug formulation, enhancing efficacy and targeting capabilities. With its robust profile, Fmoc-O-tert-butyl-L-threonine 3,4-dihydro-3-hydroxy-4-oxo-1,2,3-benzotriazine ester stands out as a key reagent for professionals in the pharmaceutical and biochemistry fields.

Synonyms
Fmoc-L-Thr(tBu)-ODhbt
CAS Number
119767-84-9
Purity
≥ 99% (HPLC)
Molecular Formula
C30H30N4O6
Molecular Weight
542.6
MDL Number
MFCD00153379
PubChem ID
14189496
Appearance
White powder
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-L-Thr(tBu)-ODhbt
CAS Number
119767-84-9
Purity
≥ 99% (HPLC)
Molecular Formula
C30H30N4O6
Molecular Weight
542.6
MDL Number
MFCD00153379
PubChem ID
14189496
Appearance
White powder
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-tert-butyl-L-threonine 3,4-dihydro-3-hydroxy-4-oxo-1,2,3-benzotriazine ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound is crucial in the synthesis of peptides, particularly in solid-phase peptide synthesis, where it serves as a protecting group for amino acids, ensuring the correct sequence and structure of peptides.
  • Drug Development: It plays a significant role in pharmaceutical research, especially in the development of peptide-based drugs, enhancing the stability and bioavailability of therapeutic agents.
  • Bioconjugation: The compound is used in bioconjugation processes, allowing researchers to attach biomolecules to surfaces or other molecules, which is essential in creating targeted drug delivery systems.
  • Analytical Chemistry: It aids in the analysis of complex biological samples, providing a means to separate and identify peptides and proteins, which is vital for understanding biological processes.
  • Research in Proteomics: This chemical is instrumental in proteomics studies, helping scientists to explore protein interactions and functions, thereby advancing our understanding of cellular mechanisms.

Citations