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Catalog Number:
05714
CAS Number:
200616-39-3
Fmoc-L-glutamic acid γ-2-phenylisopropyl ester
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-Glu(2-phenylisopropyloxy)-OH, Fmoc-L-glutamic acid 5-(2-phenylisopropyl) ester
Documents
$50.00 /100MG
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Product Information

Fmoc-L-glutamic acid g -2-phenylisopropyl ester is a versatile compound widely utilized in peptide synthesis and drug development. This amino acid derivative, characterized by its protective Fmoc (fluorenylmethyloxycarbonyl) group, offers enhanced stability and solubility, making it an ideal choice for researchers in the fields of biochemistry and medicinal chemistry. Its unique structure allows for selective coupling reactions, facilitating the formation of complex peptides with high efficiency.

In practical applications, this compound is particularly valuable in the synthesis of bioactive peptides, which are crucial for pharmaceutical research and development. Its ability to improve the yield and purity of synthesized peptides makes it a preferred reagent among professionals. Furthermore, the incorporation of the phenylisopropyl ester enhances the lipophilicity of the resulting peptides, potentially improving their bioavailability. This compound stands out in comparison to similar reagents due to its favorable handling properties and effectiveness in various coupling reactions, making it an essential tool for researchers aiming to innovate in peptide-based therapeutics.

Synonyms
Fmoc-L-Glu(2-phenylisopropyloxy)-OH, Fmoc-L-glutamic acid 5-(2-phenylisopropyl) ester
CAS Number
200616-39-3
Purity
≥ 98% (HPLC)
Molecular Formula
C29H29NO6
Molecular Weight
487.56
MDL Number
MFCD00672323
PubChem ID
76401344
Appearance
White to pale yellow glassy chunks or powder
Optical Rotation
[a]D25 = -5 ± 2 º (C=1 in MeOH)
Conditions
Store at ≤ -4 °C
General Information
Synonyms
Fmoc-L-Glu(2-phenylisopropyloxy)-OH, Fmoc-L-glutamic acid 5-(2-phenylisopropyl) ester
CAS Number
200616-39-3
Purity
≥ 98% (HPLC)
Molecular Formula
C29H29NO6
Molecular Weight
487.56
MDL Number
MFCD00672323
PubChem ID
76401344
Appearance
White to pale yellow glassy chunks or powder
Optical Rotation
[a]D25 = -5 ± 2 º (C=1 in MeOH)
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-glutamic acid g -2-phenylisopropyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex molecules for drug development and biological studies.
  • Drug Discovery: Its unique structure aids in the design of novel pharmaceuticals, particularly in targeting specific biological pathways, making it valuable in the pharmaceutical industry.
  • Bioconjugation: The compound is used in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, enhancing the efficacy of diagnostics and therapeutics.
  • Research in Neuroscience: It plays a role in studies related to neurotransmission and receptor interactions, providing insights into neurological disorders and potential treatments.
  • Protein Engineering: The compound is beneficial in modifying proteins to improve their stability and function, which is crucial for biotechnological applications and enzyme development.

Citations