Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
05699
CAS Number:
157355-79-8
Nα-Fmoc-D-histidine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-His-OH
Documents
$127.79 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

Na-Fmoc-D-histidine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which provides stability and ease of handling during the synthesis of complex peptides. Its unique structure allows for selective deprotection under mild conditions, making it an ideal choice for researchers focused on developing therapeutic peptides with high specificity and efficacy.

In the pharmaceutical industry, Na-Fmoc-D-histidine is particularly valuable for its role in the synthesis of bioactive peptides, including those used in cancer therapy and other therapeutic applications. Its ability to mimic natural amino acids while providing enhanced stability and solubility makes it a preferred choice for researchers looking to optimize peptide design. Additionally, its compatibility with various coupling reagents and solid-phase synthesis techniques further enhances its utility in both academic and industrial settings.

Synonyms
Fmoc-D-His-OH
CAS Number
157355-79-8
Purity
≥ 99% (HPLC)
Molecular Formula
C21H19N3O4
Molecular Weight
377.4
MDL Number
MFCD00237022
PubChem ID
13577227
Appearance
Off-white solid
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-D-His-OH
CAS Number
157355-79-8
Purity
≥ 99% (HPLC)
Molecular Formula
C21H19N3O4
Molecular Weight
377.4
MDL Number
MFCD00237022
PubChem ID
13577227
Appearance
Off-white solid
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-D-histidine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in peptide synthesis, enabling chemists to build complex peptides with specific sequences while preventing unwanted reactions.
  • Drug Development: It plays a crucial role in the pharmaceutical industry for developing peptide-based drugs, particularly those targeting specific receptors or enzymes, enhancing therapeutic efficacy.
  • Bioconjugation: Researchers use it in bioconjugation processes to attach biomolecules to drugs or imaging agents, improving their delivery and targeting capabilities in medical applications.
  • Protein Engineering: The compound is essential in modifying proteins, allowing scientists to create variants with enhanced stability or activity, which is vital for research in biotechnology.
  • Diagnostics: It is also utilized in the development of diagnostic tools, particularly in assays that require specific peptide recognition, contributing to advancements in personalized medicine.

Citations