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Catalog Number:
05697
CAS Number:
109745-15-5
Fmoc-D-glutamic acid-a-tert-butyl ester
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-Glu-OtBu
Documents
$55.40 /250MG
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Product Information

Fmoc-D-glutamic acid-a-tert-butyl ester is a versatile compound widely utilized in peptide synthesis and drug development. This protected amino acid derivative features a fluorenylmethoxycarbonyl (Fmoc) group, which provides stability and ease of handling during the synthesis process. Its unique tert-butyl ester group enhances solubility and reactivity, making it an ideal choice for researchers focused on the development of complex peptides and proteins. The compound's structure allows for selective deprotection, facilitating the incorporation of D-glutamic acid into peptide chains, which is crucial for various applications in medicinal chemistry and biochemistry.

In addition to its role in peptide synthesis, Fmoc-D-glutamic acid-a-tert-butyl ester is also valuable in the production of pharmaceuticals and biologically active compounds. Its ability to serve as a building block for more complex molecules opens up possibilities in drug design, particularly in the development of therapeutics targeting neurological disorders, where glutamic acid plays a significant role. Researchers and industry professionals will find this compound beneficial for its efficiency and effectiveness in producing high-purity peptides, ultimately advancing their projects in drug discovery and development.

Synonyms
Fmoc-D-Glu-OtBu
CAS Number
109745-15-5
Purity
≥ 99% (HPLC)
Molecular Formula
C24H27NO6
Molecular Weight
425.5
MDL Number
MFCD00077054
PubChem ID
3085670
Melting Point
104 - 111 °C
Appearance
White powder
Optical Rotation
[a]D20 = 10.5 ± 1 ° (C=1 in AcOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-Glu-OtBu
CAS Number
109745-15-5
Purity
≥ 99% (HPLC)
Molecular Formula
C24H27NO6
Molecular Weight
425.5
MDL Number
MFCD00077054
PubChem ID
3085670
Melting Point
104 - 111 °C
Appearance
White powder
Optical Rotation
[a]D20 = 10.5 ± 1 ° (C=1 in AcOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-glutamic acid-a-tert-butyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures with specific functionalities.
  • Drug Development: It plays a crucial role in the pharmaceutical industry, particularly in designing and optimizing drug candidates that target glutamate receptors, which are involved in various neurological conditions.
  • Bioconjugation: The compound is used in bioconjugation processes, enabling the attachment of biomolecules to surfaces or other molecules, enhancing the efficacy of therapeutic agents.
  • Research in Neuroscience: It aids in studying neurotransmitter systems, particularly in understanding the role of glutamate in synaptic transmission and plasticity.
  • Custom Synthesis: Researchers benefit from its versatility in custom synthesis projects, allowing for the modification of amino acids to tailor specific properties for various applications.

Citations