Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
05685
CAS Number:
118904-37-3
Fmoc-D-allo-isoleucine
Purity:
≥ 98.5% (HPLC)
Synonym(s):
Fmoc-D-allo-Ile-OH, Fmoc-(2R,3S-2-amino-3-methylpentanoic acid
Documents
$293.04 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

Fmoc-D-allo-isoleucine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure allows for efficient incorporation into peptides, making it an invaluable tool for researchers in the fields of biochemistry and medicinal chemistry. Fmoc-D-allo-isoleucine is particularly beneficial in the synthesis of cyclic peptides and peptidomimetics, where the stereochemistry of the amino acid plays a crucial role in biological activity and receptor binding.

In addition to its applications in peptide synthesis, Fmoc-D-allo-isoleucine is also explored for its potential in drug design and development, particularly in the creation of therapeutics targeting specific biological pathways. Its ability to enhance the stability and efficacy of peptide-based drugs makes it a preferred choice among professionals in pharmaceutical research. With its favorable properties and practical applications, Fmoc-D-allo-isoleucine stands out as a key compound for advancing research and innovation in peptide chemistry.

Synonyms
Fmoc-D-allo-Ile-OH, Fmoc-(2R,3S-2-amino-3-methylpentanoic acid
CAS Number
118904-37-3
Purity
≥ 98.5% (HPLC)
Molecular Formula
C21H23NO4
Molecular Weight
353.4
MDL Number
MFCD00077062
PubChem ID
100103
Melting Point
145-155 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = +12 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-allo-Ile-OH, Fmoc-(2R,3S-2-amino-3-methylpentanoic acid
CAS Number
118904-37-3
Purity
≥ 98.5% (HPLC)
Molecular Formula
C21H23NO4
Molecular Weight
353.4
MDL Number
MFCD00077062
PubChem ID
100103
Melting Point
145-155 °C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = +12 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-allo-isoleucine is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex and diverse peptide structures.
  • Drug Development: It plays a critical role in the pharmaceutical industry, aiding in the design of peptide-based drugs that can target specific biological pathways, enhancing therapeutic efficacy.
  • Bioconjugation: Researchers use it in bioconjugation processes to attach peptides to proteins or other molecules, which is essential for developing targeted drug delivery systems.
  • Research in Protein Engineering: This compound is valuable in protein engineering studies, helping scientists modify protein properties to improve stability and activity, which is crucial for various applications in biotechnology.
  • Analytical Chemistry: It is used in analytical methods for characterizing peptides and proteins, providing insights into their structure and function, which is vital for quality control in biopharmaceutical production.

Citations