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Catalog Number:
05675
CAS Number:
71989-17-8
Nα-Fmoc-L-asparagine 4-nitrophenyl ester
Purity:
≥ 99% (Chiral purity)
Synonym(s):
Fmoc-L-Asn-ONp
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Product Information

Na-Fmoc-L-asparagine 4-nitrophenyl ester is a versatile compound widely utilized in peptide synthesis and bioconjugation applications. This protected amino acid derivative features a fluorenylmethoxycarbonyl (Fmoc) group, which provides stability during synthesis while allowing for selective deprotection. The presence of the 4-nitrophenyl ester enhances its reactivity, making it an excellent choice for coupling reactions in the formation of peptides and complex biomolecules. Researchers appreciate its ability to facilitate the introduction of asparagine residues into peptides, which is crucial for studying protein structure and function.

In addition to its role in peptide synthesis, Na-Fmoc-L-asparagine 4-nitrophenyl ester is also valuable in the development of drug delivery systems and targeted therapies. Its unique properties enable the creation of conjugates that can improve the bioavailability and efficacy of therapeutic agents. This compound stands out for its ease of use and compatibility with various coupling reagents, making it a preferred choice for professionals in the fields of medicinal chemistry and biochemistry.

Synonyms
Fmoc-L-Asn-ONp
CAS Number
71989-17-8
Purity
≥ 99% (Chiral purity)
Molecular Formula
C25H21N3O7
Molecular Weight
475.46
MDL Number
MFCD00063329
PubChem ID
4181618
Melting Point
184 - 188 ?C
Appearance
White powder
Optical Rotation
[a]D24 = -37 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Asn-ONp
CAS Number
71989-17-8
Purity
≥ 99% (Chiral purity)
Molecular Formula
C25H21N3O7
Molecular Weight
475.46
MDL Number
MFCD00063329
PubChem ID
4181618
Melting Point
184 - 188 ?C
Appearance
White powder
Optical Rotation
[a]D24 = -37 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-L-asparagine 4-nitrophenyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures with high specificity and efficiency.
  • Drug Development: It plays a crucial role in the pharmaceutical industry for developing new drugs, particularly in the design of peptide-based therapeutics that target specific biological pathways.
  • Bioconjugation: The compound is used in bioconjugation processes, enabling the attachment of biomolecules to surfaces or other molecules, which is essential in creating targeted drug delivery systems.
  • Research in Protein Engineering: It aids in the modification of proteins, allowing scientists to study protein interactions and functions, which is vital in understanding diseases and developing treatments.
  • Diagnostic Applications: This chemical is also utilized in the development of diagnostic tools, enhancing the sensitivity and specificity of assays used in clinical settings.

Citations