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Catalog Number:
05491
CAS Number:
34404-28-9
Boc-D-glutamic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-D-Glu-OH
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Product Information

Boc-D-glutamic acid is a versatile amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. Its unique structure, featuring a tert-butoxycarbonyl (Boc) protecting group, enhances its stability and solubility, making it an ideal choice for the synthesis of complex peptides and proteins. This compound is particularly valuable in the development of peptide-based therapeutics, where precise amino acid sequences are crucial for biological activity. Researchers appreciate Boc-D-glutamic acid for its ability to facilitate the formation of peptide bonds while maintaining the integrity of the glutamic acid side chain, which is essential for various biological functions.

In addition to its applications in peptide synthesis, Boc-D-glutamic acid serves as a building block in the development of drug candidates and bioactive compounds. Its compatibility with various coupling reagents and methodologies allows for efficient incorporation into larger molecular frameworks. Furthermore, its role in the synthesis of cyclic peptides and other complex structures highlights its significance in medicinal chemistry and drug discovery. With its favorable properties and broad applicability, Boc-D-glutamic acid stands out as a critical component for researchers and industry professionals focused on advancing peptide-based innovations.

Synonyms
Boc-D-Glu-OH
CAS Number
34404-28-9
Purity
≥ 98% (HPLC)
Molecular Formula
C10H17NO6
Molecular Weight
247.25
MDL Number
MFCD00190790
PubChem ID
433622
Melting Point
108-115 ?C
Optical Rotation
[a]D22 = +13.5 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-D-Glu-OH
CAS Number
34404-28-9
Purity
≥ 98% (HPLC)
Molecular Formula
C10H17NO6
Molecular Weight
247.25
MDL Number
MFCD00190790
PubChem ID
433622
Melting Point
108-115 ?C
Optical Rotation
[a]D22 = +13.5 ± 2º (C=1 in MeOH)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-D-glutamic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group for amino acids during peptide synthesis, allowing for the selective modification of specific sites without affecting others.
  • Drug Development: Its structural properties make it valuable in the design of pharmaceutical compounds, particularly in creating prodrugs that enhance bioavailability.
  • Bioconjugation: Boc-D-glutamic acid is used in bioconjugation techniques, facilitating the attachment of biomolecules to surfaces or other molecules, which is crucial in diagnostics and therapeutic applications.
  • Research in Neuroscience: It plays a role in studying neurotransmitter systems, particularly in the development of glutamate analogs that can help in understanding neurological disorders.
  • Polymer Chemistry: The compound is incorporated into polymers for drug delivery systems, improving the release profiles and targeting of therapeutic agents.

Citations