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Catalog Number:
05474
CAS Number:
145881-13-6
Nα-Boc-Nω,ω'-bis-Z-D-arginine
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-D-Arg(Z)2-OH
Documents
$93.14 /250MG
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Product Information

Na-Boc-Nw,w'-bis-Z-D-arginine is a highly specialized amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound is particularly valued for its ability to enhance the stability and bioavailability of peptides, making it an essential tool for researchers in pharmaceutical and biochemical fields. Its unique structure, featuring two phenylmethoxycarbonyl groups, allows for effective protection of the amino groups during synthesis, facilitating the creation of complex peptide sequences with improved efficacy.

In practical applications, Na-Boc-Nw,w'-bis-Z-D-arginine is often utilized in the development of therapeutic peptides, especially those targeting specific receptors or pathways in the body. Its ability to provide steric hindrance and protect sensitive functional groups makes it ideal for use in solid-phase peptide synthesis. Researchers have successfully employed this compound in the design of peptides for cancer therapy and other critical medical applications, highlighting its versatility and importance in advancing drug discovery.

Synonyms
Boc-D-Arg(Z)2-OH
CAS Number
145881-13-6
Purity
≥ 98% (HPLC)
Molecular Formula
C27H34N4O8
Molecular Weight
542.6
MDL Number
MFCD00236825
PubChem ID
68224992
Melting Point
133 - 139 ?C
Appearance
White to off-white powder
Optical Rotation
[a]20D = 4 ± 2 ° (C=1 in DMF)
Conditions
Store at ≤ -4 °C
General Information
Synonyms
Boc-D-Arg(Z)2-OH
CAS Number
145881-13-6
Purity
≥ 98% (HPLC)
Molecular Formula
C27H34N4O8
Molecular Weight
542.6
MDL Number
MFCD00236825
PubChem ID
68224992
Melting Point
133 - 139 ?C
Appearance
White to off-white powder
Optical Rotation
[a]20D = 4 ± 2 ° (C=1 in DMF)
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Boc-Nw,w'-bis-Z-D-arginine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for the selective modification of amino acids without affecting others. This is crucial for creating complex peptides used in drug development.
  • Drug Development: It plays a significant role in the design of peptide-based therapeutics, particularly in targeting specific biological pathways, which can lead to more effective treatments with fewer side effects.
  • Bioconjugation: The compound is used in bioconjugation techniques, where it helps in attaching drugs to antibodies or other biomolecules, enhancing the specificity and efficacy of targeted therapies.
  • Research in Immunology: It is valuable in studies related to immune response modulation, as it can be incorporated into molecules that interact with immune cells, aiding in the development of vaccines and immunotherapies.
  • Analytical Chemistry: This chemical can be utilized in analytical methods to study protein interactions and stability, providing insights that are essential for both academic research and industrial applications.

Citations