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Catalog Number:
05462
CAS Number:
1676-90-0
Boc-L-aspartic acid β-tert-butyl ester
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Boc-L-Asp(OtBu)-OH
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Product Information

Boc-L-aspartic acid b-tert-butyl ester is a versatile compound widely utilized in peptide synthesis and pharmaceutical research. This protected form of aspartic acid features a tert-butyl ester group that enhances its stability and solubility, making it an ideal choice for various applications in organic synthesis. Researchers appreciate its role in the development of bioactive peptides, where the Boc (tert-butoxycarbonyl) protecting group allows for selective deprotection, facilitating the formation of complex peptide structures.

In addition to its applications in peptide synthesis, Boc-L-aspartic acid b-tert-butyl ester is also valuable in the production of pharmaceuticals and agrochemicals, where it serves as an intermediate in the synthesis of more complex molecules. Its unique properties, such as high purity and stability under standard laboratory conditions, make it a preferred choice for professionals seeking reliable reagents for their research and development projects. With its proven track record in various fields, this compound stands out as a crucial building block for innovative chemical solutions.

Synonyms
Boc-L-Asp(OtBu)-OH
CAS Number
1676-90-0
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C13H23NO6
Molecular Weight
289.4
MDL Number
MFCD00076912
PubChem ID
4089981
Melting Point
50 - 65 °C
Appearance
White powder
Optical Rotation
[a]D20 = 2.5 ± 1 ° (C = 1 in MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Boc-L-Asp(OtBu)-OH
CAS Number
1676-90-0
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C13H23NO6
Molecular Weight
289.4
MDL Number
MFCD00076912
PubChem ID
4089981
Melting Point
50 - 65 °C
Appearance
White powder
Optical Rotation
[a]D20 = 2.5 ± 1 ° (C = 1 in MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-aspartic acid b-tert-butyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create specific sequences for studies in biochemistry and pharmacology.
  • Drug Development: It plays a crucial role in the development of pharmaceutical compounds, particularly those targeting neurological disorders, by facilitating the design of molecules that can cross the blood-brain barrier.
  • Bioconjugation: The chemical is used in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, enhancing the efficacy of diagnostics and therapeutics.
  • Research in Protein Engineering: It aids in the modification of proteins, allowing scientists to study structure-function relationships and improve the stability and activity of therapeutic proteins.
  • Analytical Chemistry: The compound is utilized in analytical methods to quantify amino acids and peptides, providing essential data for various research applications.

Citations