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Catalog Number:
05459
CAS Number:
42002-18-6
Nα-Boc-L-asparagine N-hydroxysuccinimide ester
Purity:
≥ 99% (TLC)
Synonym(s):
Boc-L-Asn-OSu
Documents
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Product Information

Na-Boc-L-asparagine N-hydroxysuccinimide ester is a versatile compound widely utilized in peptide synthesis and bioconjugation applications. This compound features a Boc (tert-butyloxycarbonyl) protecting group, which is crucial for the selective protection of amino acids during synthetic processes. Its unique structure allows for efficient coupling reactions, making it an ideal choice for researchers focused on developing complex peptides and proteins. The N-hydroxysuccinimide ester functionality enhances the reactivity of the asparagine residue, facilitating the formation of stable amide bonds with various nucleophiles, including amino acids and peptides.

This compound is particularly beneficial in the pharmaceutical and biotechnology industries, where it can be employed in the design of therapeutic peptides and drug delivery systems. Its ability to improve solubility and stability of peptide constructs makes it a valuable tool for researchers aiming to optimize the pharmacokinetic properties of their compounds. Additionally, Na-Boc-L-asparagine N-hydroxysuccinimide ester stands out for its compatibility with a range of reaction conditions, providing flexibility in synthetic strategies.

Synonyms
Boc-L-Asn-OSu
CAS Number
42002-18-6
Purity
≥ 99% (TLC)
Molecular Formula
C13H19N3O7
Molecular Weight
329.31
MDL Number
MFCD00190785
PubChem ID
302431
Appearance
White powder
Optical Rotation
[a]D24 = -33.1 ± 2º (C=1% in Acetone)
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-L-Asn-OSu
CAS Number
42002-18-6
Purity
≥ 99% (TLC)
Molecular Formula
C13H19N3O7
Molecular Weight
329.31
MDL Number
MFCD00190785
PubChem ID
302431
Appearance
White powder
Optical Rotation
[a]D24 = -33.1 ± 2º (C=1% in Acetone)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Boc-L-asparagine N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, allowing researchers to create complex structures with specific amino acid sequences for various applications in drug development.
  • Bioconjugation: It is used in bioconjugation processes, where it helps to link biomolecules, such as proteins and antibodies, to therapeutic agents, enhancing the efficacy of targeted drug delivery systems.
  • Protein Modification: The ester functionality allows for selective modification of proteins, which can be crucial in studying protein interactions and functions, thereby aiding in the development of new therapeutic strategies.
  • Diagnostic Applications: This compound can be employed in the development of diagnostic assays, particularly in the field of immunology, where it helps in the labeling of antigens or antibodies for detection purposes.
  • Research in Neuroscience: It is also used in neuroscience research to study the role of asparagine in neurotransmission, providing insights into potential treatments for neurological disorders.

Citations