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Catalog Number:
05349
CAS Number:
118609-38-4
Fmoc-D-threonine
Purity:
≥ 97% (HPLC)
Synonym(s):
Fmoc-D-Thr-OH
Documents
$18.53 /1G
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Product Information

Fmoc-D-threonine is a valuable amino acid derivative widely utilized in peptide synthesis and drug development. This compound, recognized for its role as a building block in the formation of peptides, features a fluorenylmethyloxycarbonyl (Fmoc) protecting group that enhances its stability and reactivity. Its unique structure allows for selective deprotection, making it an essential component in solid-phase peptide synthesis (SPPS). Researchers and industry professionals appreciate Fmoc-D-threonine for its ability to facilitate the incorporation of threonine residues into peptides, which can be crucial for the development of therapeutic agents and biologically active compounds.

In addition to its applications in peptide synthesis, Fmoc-D-threonine is also employed in the study of protein interactions and structure-function relationships. Its versatility and effectiveness in various synthetic pathways make it a preferred choice for chemists and biochemists aiming to create complex peptide libraries or optimize drug candidates. With its reliable performance and compatibility with standard laboratory protocols, Fmoc-D-threonine stands out as a key reagent in modern chemical research and pharmaceutical development.

Synonyms
Fmoc-D-Thr-OH
CAS Number
118609-38-4
Purity
≥ 97% (HPLC)
Molecular Formula
C19H19NO5
Molecular Weight
341.4
MDL Number
MFCD00153365
Melting Point
95 - 97 ?C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = +16 ± 1 º (C=1 in DMF) [a]D20 = +5.0 to +7.0º (C=1 in MeOH)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-Thr-OH
CAS Number
118609-38-4
Purity
≥ 97% (HPLC)
Molecular Formula
C19H19NO5
Molecular Weight
341.4
MDL Number
MFCD00153365
Melting Point
95 - 97 ?C
Appearance
White to off-white powder
Optical Rotation
[a]D20 = +16 ± 1 º (C=1 in DMF) [a]D20 = +5.0 to +7.0º (C=1 in MeOH)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-D-threonine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create specific sequences for studying protein interactions and functions.
  • Drug Development: Its role in medicinal chemistry helps in designing and optimizing peptide-based drugs, particularly for targeting specific diseases, enhancing therapeutic efficacy.
  • Bioconjugation: Fmoc-D-threonine is used in bioconjugation processes, enabling the attachment of biomolecules to surfaces or other molecules, which is crucial in developing biosensors and targeted drug delivery systems.
  • Research in Protein Engineering: This compound aids in the modification of proteins, allowing scientists to explore structure-function relationships and improve protein stability and activity.
  • Analytical Chemistry: It is employed in various analytical techniques, such as chromatography, to separate and identify complex mixtures, providing valuable insights into molecular interactions.

Citations