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Catalog Number:
05336
Fmoc-O-tert-butyl-transL-hydroxyproline 4-alkoxybenzyl alcohol resin
Synonym(s):
Fmoc-L-Hyp(tBu)-Wang resin
Documents
$60.39 /1G
Pack Size Availability Price
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Product Information

Fmoc-O-tert-butyl-transL-hydroxyproline 4-alkoxybenzyl alcohol resin is a versatile compound widely utilized in peptide synthesis and drug development. This resin combines the protective Fmoc group with a tert-butyl moiety, enhancing stability and solubility during chemical reactions. Its unique structure allows for efficient coupling reactions, making it an essential tool for researchers in the fields of medicinal chemistry and biochemistry. The incorporation of 4-alkoxybenzyl alcohol further improves the resin's performance, facilitating the purification of synthesized peptides through solid-phase extraction techniques.

This compound is particularly beneficial for those involved in the synthesis of complex peptides and proteins, as it provides a reliable platform for the sequential addition of amino acids. Its ability to withstand harsh reaction conditions while maintaining high yields makes it a preferred choice among professionals. Additionally, the use of this resin can lead to improved purity and yield of final products, which is crucial for pharmaceutical applications. Researchers can leverage its unique properties to streamline their workflows and enhance the efficiency of their synthetic processes.

Synonyms
Fmoc-L-Hyp(tBu)-Wang resin
MDL Number
MFCD01634903
Substitution
0.3-0.8 meq/g
Mesh Size
100-200 mesh
Conditions
Store at 0-8°C
%DVB
1% DVB
General Information
Synonyms
Fmoc-L-Hyp(tBu)-Wang resin
MDL Number
MFCD01634903
Substitution
0.3-0.8 meq/g
Mesh Size
100-200 mesh
Conditions
Store at 0-8°C
%DVB
1% DVB
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-tert-butyl-transL-hydroxyproline 4-alkoxybenzyl alcohol resin is widely utilized in research focused on:

  • Peptide Synthesis: This resin is essential in solid-phase peptide synthesis, allowing for the efficient assembly of peptides with high purity and yield.
  • Drug Development: It plays a crucial role in the development of peptide-based therapeutics, enabling researchers to create targeted drugs for various diseases.
  • Bioconjugation: The resin facilitates the conjugation of peptides to other biomolecules, enhancing the effectiveness of drug delivery systems.
  • Research in Structural Biology: It aids in the preparation of peptides for X-ray crystallography and NMR studies, helping scientists understand protein structures.
  • Customization of Peptide Libraries: This resin allows for the creation of diverse peptide libraries, which are invaluable in screening for new drug candidates and understanding biological interactions.

Citations