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Catalog Number:
05326
CAS Number:
130878-68-1
Fmoc-L-valine N-hydroxysuccinimide ester
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-Val-OSu
Documents
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Product Information

Fmoc-L-valine N-hydroxysuccinimide ester is a versatile compound widely utilized in peptide synthesis and drug development. This compound serves as a valuable building block in the creation of peptides, particularly in solid-phase peptide synthesis (SPPS), where it enhances the efficiency and yield of the desired products. Its unique structure, featuring the Fmoc protecting group, allows for selective deprotection under mild conditions, making it an ideal choice for researchers aiming to construct complex peptide sequences with precision.

Moreover, the N-hydroxysuccinimide ester functionality facilitates the formation of stable amide bonds, which is crucial in bioconjugation applications, including the development of peptide-based therapeutics and targeted drug delivery systems. The compound's high reactivity and compatibility with various coupling reagents further enhance its appeal in both academic and industrial settings. Researchers and industry professionals can leverage Fmoc-L-valine N-hydroxysuccinimide ester to streamline their synthesis processes and improve the overall quality of their peptide products.

Synonyms
Fmoc-L-Val-OSu
CAS Number
130878-68-1
Purity
≥ 99% (HPLC)
Molecular Formula
C24H24N2O6
Molecular Weight
436.5
MDL Number
MFCD00153370
PubChem ID
20643471
Melting Point
135 - 146 ºC
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -32 ± 3 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Val-OSu
CAS Number
130878-68-1
Purity
≥ 99% (HPLC)
Molecular Formula
C24H24N2O6
Molecular Weight
436.5
MDL Number
MFCD00153370
PubChem ID
20643471
Melting Point
135 - 146 ºC
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -32 ± 3 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-valine N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the solid-phase synthesis of peptides, allowing for the efficient coupling of amino acids and enhancing the purity of the final product.
  • Drug Development: It is used in the creation of peptide-based pharmaceuticals, where its stability and reactivity facilitate the design of novel therapeutic agents.
  • Bioconjugation: The compound is instrumental in bioconjugation techniques, enabling the attachment of peptides to various biomolecules, which is crucial for developing targeted drug delivery systems.
  • Research in Proteomics: It aids in the study of protein interactions and functions, providing researchers with tools to modify proteins for better analysis and understanding of biological processes.
  • Diagnostics: This chemical plays a role in the development of diagnostic assays, where it can be used to label peptides for enhanced detection and quantification in various biological samples.

Citations