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Catalog Number:
05188
CAS Number:
84418-43-9
N-(9-Fluorenylmethoxycarbonyl)amide
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-NH2, 9-Fluorenylmethyl carbamate
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Product Information

N-(9-Fluorenylmethoxycarbonyl)amide, also known as 9H-fluoren-9-ylmethyl carbamate, is a versatile compound widely utilized in organic synthesis and peptide chemistry. This protective group is particularly valuable for researchers looking to enhance the stability and solubility of amines during chemical reactions. Its unique structure allows for easy removal under mild conditions, making it an ideal choice for protecting amino groups in the synthesis of peptides and other complex molecules.

In addition to its role in peptide synthesis, N-(9-Fluorenylmethoxycarbonyl)amide is also employed in the development of pharmaceuticals and agrochemicals, where it aids in the formation of intricate molecular architectures. Its compatibility with various reaction conditions and its ability to improve the yield of desired products make it a preferred choice among chemists. With its proven effectiveness and reliability, this compound is essential for advancing research and development in both academic and industrial settings.

Synonyms
Fmoc-NH2, 9-Fluorenylmethyl carbamate
CAS Number
84418-43-9
Purity
≥ 99% (HPLC)
Molecular Formula
C15H13NO2
Molecular Weight
239.27
MDL Number
MFCD00237376
PubChem ID
736301
Melting Point
198 - 207 °C
Appearance
White powder or white crystalline powder
Conditions
Store at ≤ -4 °C
General Information
Synonyms
Fmoc-NH2, 9-Fluorenylmethyl carbamate
CAS Number
84418-43-9
Purity
≥ 99% (HPLC)
Molecular Formula
C15H13NO2
Molecular Weight
239.27
MDL Number
MFCD00237376
PubChem ID
736301
Melting Point
198 - 207 °C
Appearance
White powder or white crystalline powder
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

N-(9-Fluorenylmethoxycarbonyl)amide is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group for amino acids during peptide synthesis, enhancing the efficiency of the process and ensuring high purity of the final product.
  • Drug Development: It is used in the development of pharmaceuticals, particularly in the design of prodrugs that improve solubility and bioavailability, leading to more effective treatments.
  • Bioconjugation: The compound facilitates the attachment of biomolecules to surfaces or other molecules, which is crucial in creating targeted drug delivery systems and diagnostic tools.
  • Research in Organic Chemistry: It plays a significant role in organic synthesis, allowing chemists to explore new reactions and develop innovative methodologies in laboratory settings.
  • Polymer Chemistry: This chemical is employed in the synthesis of polymers, contributing to the creation of materials with specific properties for applications in coatings, adhesives, and more.

Citations