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Catalog Number:
05097
CAS Number:
1423018-08-9
Fmoc-O-benzyl-L-threonyl chloride
Purity:
≥ 97%
Synonym(s):
Fmoc-L-Thr(Bzl)-Cl
Documents
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Product Information

Fmoc-O-benzyl-L-threonyl chloride is a versatile reagent widely utilized in peptide synthesis and organic chemistry. This compound serves as a protective group for amino acids, particularly in the synthesis of peptides where selective deprotection is essential. Its unique structure allows for efficient coupling reactions, making it a preferred choice among researchers aiming to create complex peptide sequences. The presence of the Fmoc group facilitates easy removal under mild basic conditions, ensuring that the integrity of the peptide chain is maintained throughout the synthesis process.

In addition to its role in peptide synthesis, Fmoc-O-benzyl-L-threonyl chloride is also valuable in the development of pharmaceuticals and biologically active compounds. Its ability to enhance solubility and stability of intermediates makes it an attractive option for medicinal chemists. Researchers can leverage this compound to streamline their workflows, reduce reaction times, and improve yields in peptide-based drug development. With its proven efficacy and reliability, Fmoc-O-benzyl-L-threonyl chloride stands out as an essential tool for professionals in the fields of biochemistry and pharmaceutical research.

Synonyms
Fmoc-L-Thr(Bzl)-Cl
CAS Number
1423018-08-9
Purity
≥ 97%
Molecular Formula
C26H24NO4Cl
Molecular Weight
449.9
MDL Number
MFCD00235834
PubChem ID
130145863
Melting Point
93-100 °C
Appearance
Off-white powder
Optical Rotation
[α]D = -4 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-Thr(Bzl)-Cl
CAS Number
1423018-08-9
Purity
≥ 97%
Molecular Formula
C26H24NO4Cl
Molecular Weight
449.9
MDL Number
MFCD00235834
PubChem ID
130145863
Melting Point
93-100 °C
Appearance
Off-white powder
Optical Rotation
[α]D = -4 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-benzyl-L-threonyl chloride is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key reagent in the synthesis of peptides, allowing researchers to create complex molecules for drug development and biological studies.
  • Protein Modification: It is used to modify proteins, enhancing their stability and functionality, which is crucial in biochemistry and pharmaceutical applications.
  • Bioconjugation: The chemical facilitates the attachment of biomolecules to surfaces or other molecules, aiding in the development of targeted drug delivery systems.
  • Research in Therapeutics: Its application in creating therapeutic peptides has significant implications in treating various diseases, including cancer and metabolic disorders.
  • Analytical Chemistry: Fmoc-O-benzyl-L-threonyl chloride is employed in analytical techniques to study protein interactions and behaviors, providing insights into biological processes.

Citations