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Catalog Number:
05074
CAS Number:
143824-77-5
Nα-Fmoc-Nω,Nω'-bis-Boc-L-arginine
Purity:
≥ 93% (HPLC)
Synonym(s):
Fmoc-L-Arg(Boc)2-OH
Documents
$85.00 /250MG
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Product Information

Na-Fmoc-Nw,Nw'-bis-Boc-L-arginine is a versatile and highly valuable compound in the field of peptide synthesis and biochemistry. This protected amino acid derivative is particularly useful for researchers involved in the development of peptide-based therapeutics and biomolecules. Its unique structure, featuring both Fmoc and Boc protecting groups, allows for selective deprotection under mild conditions, facilitating the synthesis of complex peptides with high purity and yield. This compound is commonly employed in solid-phase peptide synthesis (SPPS), where it enhances the efficiency of coupling reactions and minimizes side reactions, making it an ideal choice for professionals aiming to streamline their peptide synthesis workflows.

In addition to its application in peptide synthesis, Na-Fmoc-Nw,Nw'-bis-Boc-L-arginine has shown potential in the development of drug delivery systems and targeted therapies. Its ability to form stable conjugates with various biomolecules opens avenues for innovative therapeutic strategies, particularly in cancer and metabolic disorders. Researchers will appreciate its compatibility with various coupling reagents and its role in improving the solubility and bioavailability of peptide drugs. With its favorable properties and practical applications, this compound stands out as a crucial tool for advancing peptide chemistry and drug development.

Synonyms
Fmoc-L-Arg(Boc)2-OH
CAS Number
143824-77-5
Purity
≥ 93% (HPLC)
Molecular Formula
C31H40N4O8
Molecular Weight
596.7
MDL Number
MFCD00237008
PubChem ID
59693726
Appearance
White powder
Optical Rotation
[a]D25 = -3.3 ± 1 º (C=1 in DMF)
Conditions
Store at ≤ -15 °C
General Information
Synonyms
Fmoc-L-Arg(Boc)2-OH
CAS Number
143824-77-5
Purity
≥ 93% (HPLC)
Molecular Formula
C31H40N4O8
Molecular Weight
596.7
MDL Number
MFCD00237008
PubChem ID
59693726
Appearance
White powder
Optical Rotation
[a]D25 = -3.3 ± 1 º (C=1 in DMF)
Conditions
Store at ≤ -15 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Nw,Nw'-bis-Boc-L-arginine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex and functional peptides used in drug development.
  • Bioconjugation: It is employed in bioconjugation processes, where it helps attach peptides to other biomolecules, enhancing the specificity and efficacy of therapeutic agents in targeted drug delivery systems.
  • Research in Cancer Therapeutics: The compound's ability to modify peptides makes it valuable in developing cancer therapeutics, where tailored peptides can target cancer cells more effectively than traditional treatments.
  • Vaccine Development: In vaccine research, it aids in the design of peptide-based vaccines, which can elicit stronger immune responses by mimicking pathogen structures.
  • Protein Engineering: This chemical is crucial in protein engineering, allowing researchers to create modified proteins with enhanced stability and activity for various applications in biotechnology and pharmaceuticals.

Citations