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Catalog Number:
05043
CAS Number:
117322-30-2
Fmoc-cycloleucine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-1-aminocyclopentane-1-carboxylic acid, Fmoc-1-amino-1-carboxycyclopentane
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$29.34 /1G
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Product Information

Fmoc-cycloleucine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethyloxycarbonyl) group, which facilitates the selective coupling of amino acids during solid-phase peptide synthesis. Its unique cyclopentane structure enhances the conformational flexibility of peptides, making it an excellent choice for researchers aiming to create cyclic peptides or study structure-activity relationships. Fmoc-cycloleucine is particularly valuable in the pharmaceutical industry for developing novel therapeutics, as it can improve the stability and bioavailability of peptide-based drugs.

In addition to its applications in peptide synthesis, Fmoc-cycloleucine is also employed in the design of biomaterials and drug delivery systems. Its ability to form stable interactions with various biological molecules allows for the development of targeted therapies and diagnostic tools. Researchers appreciate its ease of use and compatibility with standard peptide synthesis protocols, making it an essential component for those working in medicinal chemistry and biochemistry. With its unique properties and practical applications, Fmoc-cycloleucine stands out as a key compound for advancing peptide research and development.

Synonyms
Fmoc-1-aminocyclopentane-1-carboxylic acid, Fmoc-1-amino-1-carboxycyclopentane
CAS Number
117322-30-2
Purity
≥ 99% (HPLC)
Molecular Formula
C21H21NO4
Molecular Weight
351.4
MDL Number
MFCD01074696
PubChem ID
978345
Melting Point
182 - 191 °C
Appearance
White to off-white powder
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-1-aminocyclopentane-1-carboxylic acid, Fmoc-1-amino-1-carboxycyclopentane
CAS Number
117322-30-2
Purity
≥ 99% (HPLC)
Molecular Formula
C21H21NO4
Molecular Weight
351.4
MDL Number
MFCD01074696
PubChem ID
978345
Melting Point
182 - 191 °C
Appearance
White to off-white powder
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-cycloleucine is widely utilized in research focused on

  • Peptide Synthesis: It serves as a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides with high purity and yield.
  • Drug Development: This compound is used in the design of peptide-based therapeutics, particularly in oncology and infectious diseases, enhancing the efficacy of drug candidates.
  • Bioconjugation: Fmoc-cycloleucine can be employed in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other molecules for targeted drug delivery.
  • Research in Protein Folding: It aids in studying protein folding and stability, providing insights into the structural dynamics of proteins, which is crucial for understanding diseases.
  • Custom Synthesis: Researchers utilize it for custom synthesis of modified peptides, enabling the exploration of new biological activities and therapeutic potentials.

Citations