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Catalog Number:
05007
CAS Number:
55750-63-5
6-Maleimidohexanoic acid N-hydroxysuccinimide ester
Purity:
≥ 98% (HPLC)
Synonym(s):
6-Maleimidocaproic acid N-hydroxysuccinimide ester, EMCS
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Product Information

6-Maleimidohexanoic acid N-hydroxysuccinimide ester is a versatile compound widely utilized in bioconjugation and protein labeling applications. This compound features a maleimide functional group, which allows for selective conjugation to thiol-containing molecules, making it an essential tool in the development of targeted drug delivery systems and diagnostic assays. Its N-hydroxysuccinimide (NHS) ester functionality enhances the stability and reactivity of the compound, facilitating efficient coupling reactions with amine-containing biomolecules.

Researchers and industry professionals benefit from the compound's ability to create stable linkages in a variety of applications, including the synthesis of antibody-drug conjugates and the development of biosensors. The unique properties of 6-Maleimidohexanoic acid N-hydroxysuccinimide ester enable precise control over the conjugation process, leading to improved performance in therapeutic and diagnostic settings. Its ease of use and effectiveness make it a preferred choice for those looking to enhance their research and development efforts in biochemistry and molecular biology.

Synonyms
6-Maleimidocaproic acid N-hydroxysuccinimide ester, EMCS
CAS Number
55750-63-5
Purity
≥ 98% (HPLC)
Molecular Formula
C14H16N2O6
Molecular Weight
308.3
MDL Number
MFCD00043043
PubChem ID
5091655
Melting Point
66 - 74 ºC (Lit.)
Appearance
White to off-white solid or crystalline powder
Conditions
Store at ≤ -4 °C
General Information
Synonyms
6-Maleimidocaproic acid N-hydroxysuccinimide ester, EMCS
CAS Number
55750-63-5
Purity
≥ 98% (HPLC)
Molecular Formula
C14H16N2O6
Molecular Weight
308.3
MDL Number
MFCD00043043
PubChem ID
5091655
Melting Point
66 - 74 ºC (Lit.)
Appearance
White to off-white solid or crystalline powder
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

6-Maleimidohexanoic acid N-hydroxysuccinimide ester is widely utilized in research focused on:

  • Bioconjugation: This compound is essential for linking biomolecules, such as proteins and antibodies, to various surfaces or labels, enhancing the development of targeted therapies and diagnostics.
  • Drug Delivery Systems: It plays a crucial role in creating drug delivery vehicles that improve the stability and efficacy of therapeutic agents, particularly in cancer treatment.
  • Diagnostic Assays: The compound is used in the formulation of assays for detecting specific biomolecules, aiding in disease diagnosis and monitoring.
  • Protein Engineering: It facilitates the modification of proteins to study their functions and interactions, which is vital for advancing biochemistry and molecular biology.
  • Surface Functionalization: This chemical is applied in modifying surfaces of materials to enhance their biocompatibility, which is important in medical device manufacturing.

Citations