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Catalog Number:
04999
CAS Number:
204322-23-6
Fmoc-L-1,2,3,4-tetrahydronorharman-3-carboxylic acid
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-Tpi-OH, Fmoc-Tpi-OH
Documents
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Product Information

Fmoc-L-1,2,3,4-tetrahydronorharman-3-carboxylic acid is a versatile compound widely utilized in peptide synthesis and medicinal chemistry. This compound features the Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which is essential for the selective protection of amines during the synthesis of peptides. Its unique structure allows for efficient incorporation into various peptide sequences, making it an invaluable tool for researchers focused on developing novel therapeutics.

In addition to its role in peptide synthesis, Fmoc-L-1,2,3,4-tetrahydronorharman-3-carboxylic acid has shown potential in the development of bioactive molecules, particularly in the field of drug discovery. Its ability to facilitate the formation of complex structures can lead to the creation of compounds with enhanced biological activity. Researchers in pharmaceutical and biochemistry sectors will find this compound particularly beneficial for its ease of use and effectiveness in generating high-purity peptides, which are crucial for biological assays and therapeutic applications.

Synonyms
Fmoc-L-Tpi-OH, Fmoc-Tpi-OH
CAS Number
204322-23-6
Purity
≥ 99% (HPLC)
Molecular Formula
C27H22N2O4
Molecular Weight
438.49
MDL Number
MFCD00673786
PubChem ID
4523701
Appearance
White to off-white powder
Optical Rotation
[a]20D = 55 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Tpi-OH, Fmoc-Tpi-OH
CAS Number
204322-23-6
Purity
≥ 99% (HPLC)
Molecular Formula
C27H22N2O4
Molecular Weight
438.49
MDL Number
MFCD00673786
PubChem ID
4523701
Appearance
White to off-white powder
Optical Rotation
[a]20D = 55 ± 2 ° (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-1,2,3,4-tetrahydronorharman-3-carboxylic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: It is used in the design of novel pharmaceuticals, particularly in the development of compounds targeting neurological disorders, due to its structural similarity to biologically active molecules.
  • Bioconjugation: The chemical facilitates bioconjugation processes, enabling the attachment of biomolecules to therapeutic agents, which enhances drug delivery and efficacy.
  • Research in Neuroscience: Its unique structure makes it a valuable tool in neuroscience research, helping scientists explore the mechanisms of neuroactive compounds and their potential therapeutic effects.
  • Analytical Chemistry: The compound is employed in analytical methods to study interactions between biomolecules, providing insights into molecular behavior and aiding in the development of new analytical techniques.

Citations