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Catalog Number:
04996
CAS Number:
215600-05-8
Fmoc-4-diethylphosphomethyl-D-phenylalanine
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-D-Phe(4-CH2PO3Et2)-OH
Documents
$113.87 /100MG
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Product Information

Fmoc-4-diethylphosphomethyl-D-phenylalanine is a versatile amino acid derivative that plays a crucial role in peptide synthesis and drug development. This compound features a unique phosphonate group, which enhances its reactivity and stability, making it an excellent choice for researchers focused on developing novel therapeutic peptides. Its Fmoc (fluorenylmethyloxycarbonyl) protecting group allows for easy incorporation into peptide chains while facilitating selective deprotection, streamlining the synthesis process.

This compound is particularly valuable in the fields of medicinal chemistry and biochemistry, where it can be utilized to create phosphopeptides that mimic natural signaling pathways. Its applications extend to the development of targeted drug delivery systems and the study of protein interactions, providing researchers with a powerful tool for advancing their work. The unique properties of Fmoc-4-diethylphosphomethyl-D-phenylalanine not only enhance the efficiency of peptide synthesis but also open new avenues for innovative research in drug design and development.

Synonyms
Fmoc-D-Phe(4-CH2PO3Et2)-OH
CAS Number
215600-05-8
Purity
≥ 99% (HPLC)
Molecular Formula
C29H32NO7P
Molecular Weight
537.56
MDL Number
MFCD00273470
PubChem ID
3457825
Appearance
White amorphous powder
Optical Rotation
[a]D20 = +17 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-D-Phe(4-CH2PO3Et2)-OH
CAS Number
215600-05-8
Purity
≥ 99% (HPLC)
Molecular Formula
C29H32NO7P
Molecular Weight
537.56
MDL Number
MFCD00273470
PubChem ID
3457825
Appearance
White amorphous powder
Optical Rotation
[a]D20 = +17 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-4-diethylphosphomethyl-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides with high purity and yield.
  • Drug Development: Its unique structure aids in the design of novel pharmaceuticals, particularly in developing targeted therapies for various diseases, including cancer.
  • Bioconjugation: The chemical's functional groups enable efficient conjugation with biomolecules, facilitating the creation of bioconjugates for diagnostics and therapeutic applications.
  • Research in Neuroscience: It is used in studies related to neuropeptides, helping scientists understand their role in brain function and potential treatments for neurological disorders.
  • Protein Engineering: The compound is valuable in modifying proteins to enhance their stability and activity, which is crucial for biotechnological applications.

Citations