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Catalog Number:
04988
CAS Number:
146987-10-2
Nα-Fmoc-Nε-biotinyl-L-lysine
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-Lys(biotinyl)-OH
Documents
$51.18 /100MG
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Product Information

Na-Fmoc-Ne-biotinyl-L-lysine is a versatile compound widely utilized in biochemistry and molecular biology for its unique properties. This biotinylated amino acid derivative serves as a crucial building block in peptide synthesis, particularly in the development of bioconjugates and targeted drug delivery systems. Its ability to easily conjugate with various biomolecules makes it an invaluable tool for researchers aiming to study protein interactions, cellular localization, and enzyme activity. The Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for straightforward solid-phase peptide synthesis, ensuring high purity and yield of the desired peptides.

In addition to its applications in peptide synthesis, Na-Fmoc-Ne-biotinyl-L-lysine is also instrumental in the creation of biotinylated probes for affinity purification and detection assays. Its biotin component enables strong binding to avidin or streptavidin, facilitating the isolation of proteins and nucleic acids in various experimental setups. Researchers benefit from its stability and ease of use, making it a preferred choice for those working in proteomics, diagnostics, and therapeutic development. This compound not only enhances the efficiency of experimental workflows but also opens avenues for innovative research in the life sciences.

Synonyms
Fmoc-L-Lys(biotinyl)-OH
CAS Number
146987-10-2
Purity
≥ 98% (HPLC)
Molecular Formula
C31H38N4O6S
Molecular Weight
594.7
MDL Number
MFCD00270741
PubChem ID
5102536
Melting Point
181 - 184 °C
Appearance
White to off-white powder
Optical Rotation
[a]20D = 18 ± 1 º (C=1 in DMF)
Conditions
Store at 0-8°C
General Information
Synonyms
Fmoc-L-Lys(biotinyl)-OH
CAS Number
146987-10-2
Purity
≥ 98% (HPLC)
Molecular Formula
C31H38N4O6S
Molecular Weight
594.7
MDL Number
MFCD00270741
PubChem ID
5102536
Melting Point
181 - 184 °C
Appearance
White to off-white powder
Optical Rotation
[a]20D = 18 ± 1 º (C=1 in DMF)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Ne-biotinyl-L-lysine is widely utilized in research focused on:

  • Bioconjugation: This compound is essential for attaching biomolecules, such as proteins or nucleic acids, to surfaces or other molecules, enhancing the study of biological interactions.
  • Peptide Synthesis: It serves as a building block in peptide synthesis, allowing researchers to create complex peptides with specific functionalities for drug development and therapeutic applications.
  • Targeted Drug Delivery: By utilizing its biotinylation properties, it enables the targeted delivery of drugs to specific cells or tissues, improving treatment efficacy and reducing side effects.
  • Diagnostics: The compound is used in the development of diagnostic tools, such as biosensors, where its ability to bind to specific targets can enhance the sensitivity and specificity of detection methods.
  • Research in Cell Biology: It plays a crucial role in studying cellular processes by facilitating the labeling of proteins, allowing researchers to visualize and track cellular functions in real-time.

Citations