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Catalog Number:
04986
CAS Number:
198560-38-2
Fmoc-L-indoline-2-carboxylic acid
Purity:
≥ 98% (Assay)
Synonym(s):
Fmoc-L-IDC-OH, Fmoc-(2S)-indoline carboxylic acid
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Product Information

Fmoc-L-indoline-2-carboxylic acid is a versatile compound widely utilized in the field of peptide synthesis and medicinal chemistry. This compound serves as a crucial building block in the development of peptide-based pharmaceuticals, particularly in the synthesis of indole-containing peptides, which are known for their diverse biological activities. Its Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for easy and efficient deprotection under mild conditions, making it an ideal choice for researchers looking to streamline their synthetic processes.

In addition to its applications in peptide synthesis, Fmoc-L-indoline-2-carboxylic acid has shown potential in the development of novel therapeutic agents targeting various diseases, including cancer and neurological disorders. Its unique structure and properties enable researchers to explore innovative drug designs that can lead to more effective treatments. With its combination of stability, reactivity, and ease of use, this compound is an essential tool for chemists and researchers aiming to advance their work in drug discovery and development.

Synonyms
Fmoc-L-IDC-OH, Fmoc-(2S)-indoline carboxylic acid
CAS Number
198560-38-2
Purity
≥ 98% (Assay)
Molecular Formula
C24H19NO4
Molecular Weight
385.4
MDL Number
MFCD00273469
PubChem ID
4712561
Melting Point
210 - 231 °C
Appearance
White powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-IDC-OH, Fmoc-(2S)-indoline carboxylic acid
CAS Number
198560-38-2
Purity
≥ 98% (Assay)
Molecular Formula
C24H19NO4
Molecular Weight
385.4
MDL Number
MFCD00273469
PubChem ID
4712561
Melting Point
210 - 231 °C
Appearance
White powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-indoline-2-carboxylic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in solid-phase peptide synthesis, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: It plays a crucial role in the design of indole-based pharmaceuticals, which are known for their diverse biological activities, including anti-cancer and anti-inflammatory properties.
  • Organic Synthesis: Researchers use it in the synthesis of complex organic molecules, benefiting from its stability and reactivity, which facilitate the formation of intricate structures.
  • Bioconjugation: The compound is employed in bioconjugation techniques, where it helps in attaching biomolecules to surfaces or other molecules, enhancing the efficacy of drug delivery systems.
  • Analytical Chemistry: It is utilized in analytical methods to study indole derivatives, providing insights into their chemical behavior and interactions in various environments.

Citations