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Catalog Number:
04985
CAS Number:
144069-67-0
Boc-L-indoline-2-carboxylic acid
Purity:
≥ 97% (HPLC)
Synonym(s):
Boc-L-IDC-OH, Boc-(2S-indoline carboxylic acid
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Product Information

Boc-L-indoline-2-carboxylic acid is a versatile compound widely utilized in the fields of organic synthesis and medicinal chemistry. This compound, characterized by its unique structure, serves as a valuable building block for the development of various pharmaceuticals and bioactive molecules. Its Boc (tert-butyloxycarbonyl) protecting group enhances its stability and solubility, making it an ideal candidate for peptide synthesis and other complex organic reactions. Researchers often leverage this compound in the synthesis of indole derivatives, which are known for their diverse biological activities, including anti-inflammatory and anticancer properties.

In addition to its role in synthetic chemistry, Boc-L-indoline-2-carboxylic acid is recognized for its potential applications in drug discovery and development. Its ability to facilitate the formation of intricate molecular architectures allows for the exploration of new therapeutic agents. The compound's favorable properties, such as its ease of handling and compatibility with various reaction conditions, make it a preferred choice among chemists and researchers seeking to innovate in the pharmaceutical landscape.

Synonyms
Boc-L-IDC-OH, Boc-(2S-indoline carboxylic acid
CAS Number
144069-67-0
Purity
≥ 97% (HPLC)
Molecular Formula
C14H17NO4
Molecular Weight
263.3
MDL Number
MFCD00273433
PubChem ID
2794663
Appearance
Off-white solid
Optical Rotation
[a]D20 = -81 ± 2º (C=1.5 in CHCl3 or DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-L-IDC-OH, Boc-(2S-indoline carboxylic acid
CAS Number
144069-67-0
Purity
≥ 97% (HPLC)
Molecular Formula
C14H17NO4
Molecular Weight
263.3
MDL Number
MFCD00273433
PubChem ID
2794663
Appearance
Off-white solid
Optical Rotation
[a]D20 = -81 ± 2º (C=1.5 in CHCl3 or DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-L-indoline-2-carboxylic acid is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in creating modified amino acids that enhance the stability and bioactivity of therapeutic peptides.
  • Drug Development: It is employed in the pharmaceutical industry for the development of novel drug candidates, especially in targeting specific biological pathways, due to its unique structural properties.
  • Bioconjugation: The chemical is used in bioconjugation processes, allowing researchers to attach biomolecules to drugs or imaging agents, improving their efficacy and targeting capabilities.
  • Research in Neuroscience: Its derivatives are investigated for potential applications in neuroscience, particularly in the study of neurotransmitter systems and neuroprotective agents.
  • Material Science: Boc-L-indoline-2-carboxylic acid is also explored in the development of advanced materials, including polymers and coatings, due to its ability to enhance material properties.

Citations