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Catalog Number:
04942
CAS Number:
174148-03-9
Fmoc-(2S,4S-4-amino-1-Boc-pyrrolidine-2-carboxylic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-ABPC(2S,4S-OH
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Product Information

The compound (2S,4S)-Fmoc-4-amino-1-Boc-pyrrolidine-2-carboxylic acid is a versatile building block widely utilized in peptide synthesis and drug development. This compound features a unique combination of protective groups, namely the Fmoc (fluorenylmethyloxycarbonyl) and Boc (tert-butyloxycarbonyl), which facilitate selective reactions and enhance stability during synthesis. Its chirality and specific structural attributes make it particularly valuable in the production of complex peptides and pharmaceuticals, allowing researchers to achieve high purity and yield in their processes.

In the pharmaceutical industry, this compound is instrumental in the development of peptide-based therapeutics, where precise amino acid sequences are crucial for efficacy. Its ability to protect amino groups while allowing for further functionalization makes it an ideal candidate for researchers looking to streamline their synthetic pathways. Additionally, the compound's stability under various reaction conditions ensures reliable performance, making it a preferred choice for both academic and industrial applications.

Synonyms
Fmoc-ABPC(2S,4S-OH
CAS Number
174148-03-9
Purity
≥ 98% (HPLC)
Molecular Formula
C25H28N2O6
Molecular Weight
452.5
MDL Number
MFCD00673782
PubChem ID
3671690
Appearance
White to off-white powder
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-ABPC(2S,4S-OH
CAS Number
174148-03-9
Purity
≥ 98% (HPLC)
Molecular Formula
C25H28N2O6
Molecular Weight
452.5
MDL Number
MFCD00673782
PubChem ID
3671690
Appearance
White to off-white powder
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(2S,4S)-Fmoc-4-amino-1-Boc-pyrrolidine-2-carboxylic acid is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the efficient assembly of complex peptide structures.
  • Drug Development: It plays a significant role in the pharmaceutical industry for developing new drugs, especially in creating peptide-based therapeutics that target specific diseases.
  • Bioconjugation: The compound is used in bioconjugation processes, facilitating the attachment of biomolecules to other molecules, which is essential in creating targeted drug delivery systems.
  • Research in Neuroscience: Researchers utilize this compound to study neuropeptides, which are crucial for understanding brain functions and developing treatments for neurological disorders.
  • Custom Synthesis Services: Many chemical suppliers offer custom synthesis services for this compound, enabling researchers to obtain tailored derivatives for specific applications in their studies.

Citations