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Catalog Number:
04903
CAS Number:
149-73-5
Trimethyl orthoformate
Purity:
≥ 99%
Synonym(s):
Orthoformic acid trimethyl ester, Trimethoxymethane, Methyl orthoformate
Hazmat
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$20.20 /100ML
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Product Information

Trimethyl orthoformate is a versatile chemical compound widely recognized for its utility in organic synthesis and as a reagent in various chemical reactions. This compound, also known as trimethoxymethane, serves as an important building block in the production of esters and other derivatives, making it invaluable in the fields of pharmaceuticals, agrochemicals, and specialty chemicals. Its unique structure allows for the efficient introduction of methoxy groups into target molecules, facilitating the development of complex organic compounds.

Researchers and industry professionals appreciate trimethyl orthoformate for its ability to act as a protective group for alcohols and amines, enhancing the selectivity and yield of reactions. Additionally, its use in the synthesis of various heterocycles and as a solvent in chemical processes underscores its relevance in modern chemistry. With its favorable reactivity profile and ease of handling, trimethyl orthoformate stands out as a preferred choice for those looking to streamline their synthetic pathways and improve overall efficiency in laboratory and industrial applications.

Synonyms
Orthoformic acid trimethyl ester, Trimethoxymethane, Methyl orthoformate
CAS Number
149-73-5
Purity
≥ 99%
Molecular Formula
C4H10O3
Molecular Weight
106.12
MDL Number
MFCD00008483
PubChem ID
9005
Density
0.970
Appearance
Colorless liquid
Boiling Point
101 - 102 ?C (Lit.)
Refractive Index
n20/D 1.379 (Lit.)
Conditions
Store at RT
General Information
Synonyms
Orthoformic acid trimethyl ester, Trimethoxymethane, Methyl orthoformate
CAS Number
149-73-5
Purity
≥ 99%
Molecular Formula
C4H10O3
Molecular Weight
106.12
MDL Number
MFCD00008483
PubChem ID
9005
Density
0.970
Appearance
Colorless liquid
Boiling Point
101 - 102 ?C (Lit.)
Refractive Index
n20/D 1.379 (Lit.)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Trimethyl orthoformate is widely utilized in research focused on:

  • Synthesis of Acetals: It serves as a key reagent in the formation of acetals, which are important in organic synthesis for protecting carbonyl groups during chemical reactions.
  • Production of Fine Chemicals: This compound is used in the manufacture of fine chemicals and pharmaceuticals, offering a versatile pathway for creating complex molecular structures.
  • Solvent Applications: Due to its solvent properties, it is employed in various chemical reactions and formulations, enhancing the solubility of reactants and improving reaction efficiency.
  • Formulation of Coatings: In the coatings industry, it is utilized to improve the durability and performance of protective coatings, providing enhanced resistance to moisture and chemicals.
  • Research in Organic Chemistry: It is a valuable tool in laboratories for researchers exploring new synthetic methodologies, allowing for innovative approaches in organic chemistry.

Citations