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Catalog Number:
04832
CAS Number:
75-89-8
Trifluoroethanol
Purity:
≥ 99% (GC)
Synonym(s):
2,2,2-Trifluoroethanol, Trifluoroethyl alcohol
Hazmat
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$18.37 /25G
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Product Information

Trifluoroethanol is a versatile solvent known for its unique properties, making it an essential compound in various industrial and research applications. This colorless liquid is characterized by its high polarity and ability to dissolve a wide range of organic and inorganic compounds, which makes it particularly valuable in chemical synthesis and analytical chemistry. Researchers often utilize trifluoroethanol in the preparation of fluorinated compounds, as well as in the study of protein structures and interactions due to its ability to stabilize certain conformations. Its low toxicity and favorable boiling point further enhance its appeal as a solvent in laboratory settings.

In addition to its role in organic synthesis, trifluoroethanol is also employed in the pharmaceutical industry for drug formulation and development. Its unique solvent properties allow for improved solubility of active pharmaceutical ingredients, leading to enhanced bioavailability. Furthermore, trifluoroethanol is utilized in the production of specialty chemicals and as a reagent in various chemical reactions, showcasing its versatility and importance across multiple sectors. With its distinct characteristics, trifluoroethanol stands out as a valuable tool for researchers and industry professionals alike.

Synonyms
2,2,2-Trifluoroethanol, Trifluoroethyl alcohol
CAS Number
75-89-8
Purity
≥ 99% (GC)
Molecular Formula
C2H3F3O
Molecular Weight
100.0
MDL Number
MFCD00004672
PubChem ID
6409
Melting Point
-44 °C (Lit.)
Density
1.373 g/mL at 25 °C
Appearance
Clear liquid
Boiling Point
77 - 80 °C (Lit.)
Refractive Index
n20/D 1.300 (Lit.)
Conditions
Store at RT
General Information
Synonyms
2,2,2-Trifluoroethanol, Trifluoroethyl alcohol
CAS Number
75-89-8
Purity
≥ 99% (GC)
Molecular Formula
C2H3F3O
Molecular Weight
100.0
MDL Number
MFCD00004672
PubChem ID
6409
Melting Point
-44 °C (Lit.)
Density
1.373 g/mL at 25 °C
Appearance
Clear liquid
Boiling Point
77 - 80 °C (Lit.)
Refractive Index
n20/D 1.300 (Lit.)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Trifluoroethanol is widely utilized in research focused on:

  • Solvent in Organic Synthesis: It serves as an excellent solvent for various organic reactions, particularly in the synthesis of fluorinated compounds, enhancing reaction rates and yields.
  • Protein Stabilization: In biochemistry, it is used to stabilize proteins and enzymes during experiments, allowing for better structural analysis and functional studies.
  • Polymer Production: The chemical is employed in the production of fluorinated polymers, which are known for their chemical resistance and thermal stability, making them ideal for high-performance applications.
  • Pharmaceutical Formulations: Trifluoroethanol is used in drug formulation processes, particularly for enhancing the solubility of certain active pharmaceutical ingredients, improving bioavailability.
  • Analytical Chemistry: It acts as a solvent in various analytical techniques, such as NMR spectroscopy, providing clearer spectra and better resolution for complex mixtures.

Citations