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Catalog Number:
04831
CAS Number:
14470-28-1
4-Methoxytriphenylmethyl chloride
Purity:
≥ 99% (Assay by titration, HPLC)
Synonym(s):
4-Methoxytrityl chloride, MMT-Cl
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Product Information

4-Methoxytrityl chloride is a versatile reagent widely utilized in organic synthesis, particularly in the field of nucleic acid chemistry. This compound serves as a protective group for hydroxyl functionalities, enabling the selective modification of nucleotides and oligonucleotides. Its ability to form stable ether linkages makes it an essential tool for researchers working on DNA and RNA synthesis, facilitating the development of various biotechnological applications, including gene therapy and molecular diagnostics.

In addition to its role in nucleic acid chemistry, 4-Methoxytrityl chloride is also employed in the synthesis of complex organic molecules, where it aids in the protection of alcohols during multi-step reactions. Its unique properties, such as high reactivity and stability under various conditions, provide significant advantages over similar protective groups, making it a preferred choice for chemists seeking efficiency and reliability in their synthetic pathways. With its broad applicability, 4-Methoxytrityl chloride continues to be a valuable asset in both academic research and industrial applications.

Synonyms
4-Methoxytrityl chloride, MMT-Cl
CAS Number
14470-28-1
Purity
≥ 99% (Assay by titration, HPLC)
Molecular Formula
C20H17ClO
Molecular Weight
308.81
MDL Number
MFCD00000814
PubChem ID
84462
Melting Point
119 - 125 °C
Appearance
White to brown crystalline powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
4-Methoxytrityl chloride, MMT-Cl
CAS Number
14470-28-1
Purity
≥ 99% (Assay by titration, HPLC)
Molecular Formula
C20H17ClO
Molecular Weight
308.81
MDL Number
MFCD00000814
PubChem ID
84462
Melting Point
119 - 125 °C
Appearance
White to brown crystalline powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Methoxytrityl chloride is widely utilized in research focused on:

  • Nucleic Acid Synthesis: It serves as a protecting group for the hydroxyl groups in nucleotides, which is crucial in the synthesis of RNA and DNA. This application is vital for genetic research and biopharmaceutical development.
  • Organic Synthesis: This compound is used in various organic synthesis processes, allowing chemists to create complex molecules efficiently. Its ability to protect functional groups enhances the selectivity and yield of reactions.
  • Pharmaceutical Development: In drug formulation, it helps in modifying the structure of active pharmaceutical ingredients (APIs) to improve their stability and bioavailability, which is essential for effective medication.
  • Material Science: The compound is applied in the development of advanced materials, including polymers and coatings, where its properties can enhance durability and performance.
  • Research Laboratories: It is commonly used in academic and industrial labs for various chemical reactions, providing researchers with a reliable tool for their experimental needs.

Citations