Fmoc-L-histidine(2-chlorotrityl resin)amide is widely utilized in research focused on:
- Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides efficiently. Its protective Fmoc group facilitates easy deprotection, making it ideal for sequential synthesis.
- Drug Development: In pharmaceutical research, it is used to develop peptide-based drugs. Its unique structure can enhance the stability and bioavailability of therapeutic peptides, which is crucial for effective treatment.
- Bioconjugation: The resin can be used in bioconjugation processes, where it helps attach peptides to other molecules, such as antibodies or drugs, improving targeted delivery systems in cancer therapy.
- Protein Engineering: Researchers utilize this compound to modify histidine residues in proteins, enabling the study of protein interactions and functions, which is essential in understanding biological processes.
- Analytical Chemistry: It plays a role in the development of analytical methods for detecting and quantifying peptides, aiding in quality control and research applications in various industries.
General Information
Properties
Safety and Regulations
Applications
Fmoc-L-histidine(2-chlorotrityl resin)amide is widely utilized in research focused on:
- Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides efficiently. Its protective Fmoc group facilitates easy deprotection, making it ideal for sequential synthesis.
- Drug Development: In pharmaceutical research, it is used to develop peptide-based drugs. Its unique structure can enhance the stability and bioavailability of therapeutic peptides, which is crucial for effective treatment.
- Bioconjugation: The resin can be used in bioconjugation processes, where it helps attach peptides to other molecules, such as antibodies or drugs, improving targeted delivery systems in cancer therapy.
- Protein Engineering: Researchers utilize this compound to modify histidine residues in proteins, enabling the study of protein interactions and functions, which is essential in understanding biological processes.
- Analytical Chemistry: It plays a role in the development of analytical methods for detecting and quantifying peptides, aiding in quality control and research applications in various industries.
Documents
Safety Data Sheets (SDS)
The SDS provides comprehensive safety information on handling, storage, and disposal of the product.
Product Specification (PS)
The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
*Catalog Number
*Lot Number
Certificates Of Origin (COO)
This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.
*Catalog Number
*Lot Number
Safety Data Sheets (SDS)
The SDS provides comprehensive safety information on handling, storage, and disposal of the product.
DownloadProduct Specification (PS)
The PS provides a comprehensive breakdown of the product’s properties, including chemical composition, physical state, purity, and storage requirements. It also details acceptable quality ranges and the product's intended applications.
DownloadCertificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
*Catalog Number
*Lot Number
Certificates Of Origin (COO)
This COO confirms the country where the product was manufactured, and also details the materials and components used in it and whether it is derived from natural, synthetic, or other specific sources. This certificate may be required for customs, trade, and regulatory compliance.