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Catalog Number:
04316
CAS Number:
350241-80-4
Fmoc-O-2-chlorotrityl-L-tyrosine
Purity:
≥ 99% (Chiral HPLC, HPLC)
Synonym(s):
Fmoc-L-Tyr(2-ClTrt)-OH
Documents
$43.87 /1G
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Product Information

Fmoc-O-2-chlorotrityl-L-tyrosine is a versatile and valuable compound widely utilized in peptide synthesis and drug development. This protected amino acid derivative features a unique chlorotrityl group that enhances its stability and reactivity, making it an ideal choice for solid-phase peptide synthesis (SPPS). Researchers appreciate its ability to facilitate the selective coupling of amino acids, allowing for the efficient construction of complex peptides. The Fmoc (9-fluorenylmethoxycarbonyl) protection group is easily removable under mild conditions, ensuring that the integrity of the peptide chain is maintained throughout the synthesis process.

This compound is particularly relevant in the pharmaceutical industry, where it plays a crucial role in the development of peptide-based therapeutics. Its application extends to the synthesis of bioactive peptides, which are essential in various biological processes and have potential uses in treating diseases such as cancer and diabetes. With its unique properties and practical applications, Fmoc-O-2-chlorotrityl-L-tyrosine stands out as a key reagent for researchers and industry professionals focused on advancing peptide chemistry.

Synonyms
Fmoc-L-Tyr(2-ClTrt)-OH
CAS Number
350241-80-4
Purity
≥ 99% (Chiral HPLC, HPLC)
Molecular Formula
C43H34NO5Cl
Molecular Weight
680.2
MDL Number
MFCD01073759
PubChem ID
75627311
Melting Point
160 - 165 °C
Appearance
White to yellow-brown powder
Optical Rotation
[a]D20 = -30 to -36 ° (C=1 in EtOAc)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-L-Tyr(2-ClTrt)-OH
CAS Number
350241-80-4
Purity
≥ 99% (Chiral HPLC, HPLC)
Molecular Formula
C43H34NO5Cl
Molecular Weight
680.2
MDL Number
MFCD01073759
PubChem ID
75627311
Melting Point
160 - 165 °C
Appearance
White to yellow-brown powder
Optical Rotation
[a]D20 = -30 to -36 ° (C=1 in EtOAc)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-2-chlorotrityl-L-tyrosine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for selective reactions while maintaining the integrity of the amino acid structure.
  • Drug Development: It plays a crucial role in the development of peptide-based drugs, enhancing the stability and efficacy of therapeutic agents.
  • Bioconjugation: The compound is used in bioconjugation processes, enabling the attachment of biomolecules to surfaces or other molecules, which is essential in diagnostics and targeted therapies.
  • Research in Neuroscience: It is valuable for synthesizing neuropeptides, which are important for studying neurological functions and developing treatments for neurodegenerative diseases.
  • Custom Peptide Libraries: Researchers utilize this compound to create diverse peptide libraries for screening potential drug candidates, facilitating faster discovery of new therapeutics.

Citations