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Catalog Number:
04160
CAS Number:
133054-21-4
Fmoc-L-thiaproline
Purity:
≥ 97% (HPLC)
Synonym(s):
Fmoc-L-Thz-OH, Fmoc-L-thiazolidine-4-carboxylic acid
Documents
$36.65 /1G
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Product Information

Fmoc-L-thiaproline is a valuable amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique thiazolidine ring structure, which enhances its stability and bioactivity compared to traditional amino acids. Its fluorenylmethoxycarbonyl (Fmoc) protecting group allows for easy incorporation into peptides, making it an essential building block for researchers in the fields of medicinal chemistry and biochemistry.

The distinct properties of Fmoc-L-thiaproline enable its application in the design of peptide-based therapeutics, particularly in the development of inhibitors and modulators for various biological targets. Its ability to mimic natural amino acids while providing enhanced structural diversity makes it a preferred choice for scientists looking to innovate in drug design. Additionally, Fmoc-L-thiaproline's compatibility with standard peptide coupling reagents further streamlines the synthesis process, ensuring efficient and reproducible results in laboratory settings.

Synonyms
Fmoc-L-Thz-OH, Fmoc-L-thiazolidine-4-carboxylic acid
CAS Number
133054-21-4
Purity
≥ 97% (HPLC)
Molecular Formula
C19H17NO4S
Molecular Weight
355.2
MDL Number
MFCD00235910
PubChem ID
5195877
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -69 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-Thz-OH, Fmoc-L-thiazolidine-4-carboxylic acid
CAS Number
133054-21-4
Purity
≥ 97% (HPLC)
Molecular Formula
C19H17NO4S
Molecular Weight
355.2
MDL Number
MFCD00235910
PubChem ID
5195877
Appearance
White to off-white powder
Optical Rotation
[a]D20 = -69 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-thiaproline is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of cyclic peptides that can exhibit enhanced biological activity.
  • Drug Development: Its unique structural properties make it a candidate for designing novel pharmaceuticals, especially in targeting specific receptors or enzymes, thus aiding in the creation of more effective drugs.
  • Bioconjugation: Fmoc-L-thiaproline is employed in bioconjugation processes, allowing researchers to attach biomolecules to surfaces or other molecules, which is crucial in creating targeted drug delivery systems.
  • Protein Engineering: This compound is useful in modifying proteins to improve their stability and functionality, making it a key player in the field of biotechnology.
  • Research in Organosulfur Chemistry: It provides insights into the behavior of sulfur-containing compounds, which is important for understanding various biochemical processes and developing new materials.

Citations