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Catalog Number:
04157
CAS Number:
2140-76-3
2'-O-Methyluridine
Purity:
≥ 99% (HPLC)
Synonym(s):
2'-O-Methyl-D-uridine
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Product Information

2'-O-Methyluridine is a modified nucleoside that plays a crucial role in various biochemical applications, particularly in the fields of molecular biology and biochemistry. This compound is recognized for its ability to enhance the stability and efficacy of RNA molecules, making it a valuable tool in RNA research and therapeutic development. Its unique structure allows for improved binding affinity and resistance to enzymatic degradation, which is essential for the design of RNA-based drugs and vaccines. Researchers utilize 2'-O-Methyluridine in the synthesis of modified RNA oligonucleotides, contributing to advancements in gene therapy and RNA interference technologies.

Additionally, this compound is instrumental in studying RNA-protein interactions and the development of RNA-based therapeutics, providing significant advantages over unmodified nucleosides. Its application in the pharmaceutical industry is expanding, particularly in the creation of mRNA vaccines, where stability and efficacy are paramount. With its proven benefits in enhancing RNA functionality, 2'-O-Methyluridine stands out as a critical component for researchers and industry professionals aiming to innovate in the rapidly evolving field of RNA biology.

Synonyms
2'-O-Methyl-D-uridine
CAS Number
2140-76-3
Purity
≥ 99% (HPLC)
Molecular Formula
C10H14N2O6
Molecular Weight
258.2
MDL Number
MFCD00056054
PubChem ID
560213
Appearance
White to off-white powder
Conditions
Store at ≤ -4°C
General Information
Synonyms
2'-O-Methyl-D-uridine
CAS Number
2140-76-3
Purity
≥ 99% (HPLC)
Molecular Formula
C10H14N2O6
Molecular Weight
258.2
MDL Number
MFCD00056054
PubChem ID
560213
Appearance
White to off-white powder
Conditions
Store at ≤ -4°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2'-O-Methyluridine is widely utilized in research focused on:

  • RNA Modification: This compound is commonly used to modify RNA molecules, enhancing their stability and resistance to degradation. This is particularly beneficial in therapeutic applications where RNA stability is crucial.
  • Antiviral Research: It plays a significant role in the development of antiviral agents. Researchers explore its potential to inhibit viral replication, making it valuable in the fight against viral infections.
  • Drug Development: In pharmaceutical research, it serves as a building block for the synthesis of nucleoside analogs, which are essential in creating new antiviral and anticancer drugs.
  • Gene Expression Studies: This compound is used in studies to understand gene expression and regulation, providing insights into cellular processes and disease mechanisms.
  • Biotechnology Applications: It is utilized in the production of modified RNA for vaccines and therapeutics, offering advantages in terms of efficacy and safety compared to traditional methods.

Citations