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Catalog Number:
04151
CAS Number:
62129-44-6
Boc-4-iodo-L-phenylalanine
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-L-Phe(4-I)-OH, Boc-p-iodo-L-Phe-OH, Boc-Phe(4-I)-OH
Documents
$18.53 /1G
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Product Information

Boc-4-iodo-L-phenylalanine is a valuable amino acid derivative widely utilized in peptide synthesis and medicinal chemistry. This compound features a protective Boc (tert-butyloxycarbonyl) group, which enhances its stability and solubility, making it an ideal choice for researchers working on complex peptide sequences. The presence of the 4-iodophenyl group not only contributes to its unique properties but also facilitates various coupling reactions, allowing for the incorporation of iodine into peptides, which can be crucial for radiolabeling in imaging studies.

In pharmaceutical research, Boc-4-iodo-L-phenylalanine serves as a building block for the development of bioactive peptides and can be instrumental in the design of novel therapeutics targeting specific biological pathways. Its application in the synthesis of peptide-based drugs highlights its significance in advancing drug discovery and development. With its favorable characteristics, this compound stands out as a versatile tool for chemists and researchers aiming to innovate in the fields of biochemistry and pharmacology.

Synonyms
Boc-L-Phe(4-I)-OH, Boc-p-iodo-L-Phe-OH, Boc-Phe(4-I)-OH
CAS Number
62129-44-6
Purity
≥ 98% (HPLC)
Molecular Formula
C14H18INO4
Molecular Weight
391.2
MDL Number
MFCD00037119
PubChem ID
3409757
Melting Point
145-150 ?C
Appearance
White powder
Optical Rotation
[a]D20 = +22.5 ± 3º (C=1% in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc-L-Phe(4-I)-OH, Boc-p-iodo-L-Phe-OH, Boc-Phe(4-I)-OH
CAS Number
62129-44-6
Purity
≥ 98% (HPLC)
Molecular Formula
C14H18INO4
Molecular Weight
391.2
MDL Number
MFCD00037119
PubChem ID
3409757
Melting Point
145-150 ?C
Appearance
White powder
Optical Rotation
[a]D20 = +22.5 ± 3º (C=1% in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-4-iodo-L-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of modified peptides that can enhance biological activity or stability.
  • Drug Development: Its unique structure allows researchers to explore new drug candidates, especially in the fields of oncology and neurology, where specific targeting of receptors is crucial.
  • Bioconjugation: The iodine atom in the compound can be used for radiolabeling, making it valuable in the development of imaging agents for diagnostic purposes in medical research.
  • Protein Engineering: This chemical is instrumental in the design of proteins with enhanced properties, aiding in the creation of therapeutic proteins that can be used in treatments.
  • Research on Amino Acid Analogues: It provides insights into the behavior of amino acid analogues, helping scientists understand their effects on biological systems and potential therapeutic applications.

Citations