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Catalog Number:
04137
CAS Number:
114873-10-8
Boc-2-fluoro-D-phenylalanine
Purity:
≥ 99% (HPLC)
Synonym(s):
Boc-D-Phe(2-F)-OH, Boc-o-fluoro-D-Phe-OH, (R-Boc-2-amino-3-(2-fluorophenyl)propionic acid
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$33.45 /1G
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Product Information

Boc-2-fluoro-D-phenylalanine is a valuable amino acid derivative widely utilized in the fields of medicinal chemistry and peptide synthesis. This compound features a unique fluorine substitution that enhances its biological activity, making it an essential building block for the development of novel pharmaceuticals. Its Boc (tert-butyloxycarbonyl) protecting group allows for easy manipulation during synthetic processes, facilitating the incorporation of this amino acid into complex peptide structures. Researchers have leveraged Boc-2-fluoro-D-phenylalanine in the design of targeted therapies, particularly in the development of inhibitors for various enzymes and receptors, showcasing its potential in drug discovery and development.

The compound's distinctive properties, including its ability to mimic natural amino acids while providing enhanced stability and reactivity, make it an attractive option for scientists aiming to create more effective therapeutic agents. Its applications extend to the synthesis of peptide-based drugs, where the incorporation of fluorinated amino acids can significantly improve pharmacokinetic profiles. With its robust performance in various synthetic pathways, Boc-2-fluoro-D-phenylalanine stands out as a crucial tool for researchers and industry professionals focused on advancing biopharmaceutical innovations.

Synonyms
Boc-D-Phe(2-F)-OH, Boc-o-fluoro-D-Phe-OH, (R-Boc-2-amino-3-(2-fluorophenyl)propionic acid
CAS Number
114873-10-8
Purity
≥ 99% (HPLC)
Molecular Formula
C14H18FNO4
Molecular Weight
283.2
MDL Number
MFCD00672521
PubChem ID
2756793
Melting Point
92-98 ºC
Appearance
White powder
Optical Rotation
-10.5±1° (c= 1% ethyl acetate)
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-D-Phe(2-F)-OH, Boc-o-fluoro-D-Phe-OH, (R-Boc-2-amino-3-(2-fluorophenyl)propionic acid
CAS Number
114873-10-8
Purity
≥ 99% (HPLC)
Molecular Formula
C14H18FNO4
Molecular Weight
283.2
MDL Number
MFCD00672521
PubChem ID
2756793
Melting Point
92-98 ºC
Appearance
White powder
Optical Rotation
-10.5±1° (c= 1% ethyl acetate)
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-2-fluoro-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of novel therapeutic agents. Its unique fluorine substitution enhances the biological activity of peptides.
  • Drug Development: Researchers leverage its properties to create fluorinated amino acids that can improve the pharmacokinetics of drug candidates, making them more effective in targeting specific biological pathways.
  • Biochemical Studies: It is used in studies investigating protein structure and function, allowing scientists to explore how modifications affect protein interactions and stability.
  • Diagnostics: The compound can be incorporated into imaging agents, enhancing the sensitivity and specificity of diagnostic techniques in medical applications.
  • Research in Neuroscience: Its application in studying neurotransmitter systems helps researchers understand the role of amino acids in brain function and the development of neuropharmacological therapies.

Citations