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Catalog Number:
04119
CAS Number:
198474-90-7
Boc-3,4-difluoro-L-phenylalanine
Purity:
≥ 98% (HPLC)
Synonym(s):
Boc-L-Phe(3,4-DiF)-OH, Boc-3,4-difluoro-L-Phe-OH, Boc-Phe(3,4-DiF)-OH
Documents
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Product Information

Boc-3,4-difluoro-L-phenylalanine is a valuable amino acid derivative known for its unique fluorinated structure, which enhances its utility in pharmaceutical research and development. This compound serves as a crucial building block in the synthesis of peptide-based drugs, particularly those targeting specific biological pathways. Its fluorine atoms contribute to increased metabolic stability and improved binding affinity, making it an attractive candidate for medicinal chemistry applications. Researchers have utilized Boc-3,4-difluoro-L-phenylalanine in the design of novel therapeutics, particularly in the development of inhibitors for various enzymes and receptors, showcasing its potential in advancing drug discovery.

In addition to its applications in drug development, Boc-3,4-difluoro-L-phenylalanine can be employed in the study of protein folding and structure-function relationships. Its incorporation into peptides allows scientists to probe the effects of fluorination on biological activity and stability. This compound stands out among similar amino acid derivatives due to its specific fluorinated properties, which can lead to enhanced performance in various biochemical assays. Overall, Boc-3,4-difluoro-L-phenylalanine is a versatile tool for researchers aiming to innovate in the fields of biochemistry and pharmacology.

Synonyms
Boc-L-Phe(3,4-DiF)-OH, Boc-3,4-difluoro-L-Phe-OH, Boc-Phe(3,4-DiF)-OH
CAS Number
198474-90-7
Purity
≥ 98% (HPLC)
Molecular Formula
C14H17F2NO4
Molecular Weight
301.3
MDL Number
MFCD00672518
PubChem ID
2756792
Conditions
Store at 0-8°C
General Information
Synonyms
Boc-L-Phe(3,4-DiF)-OH, Boc-3,4-difluoro-L-Phe-OH, Boc-Phe(3,4-DiF)-OH
CAS Number
198474-90-7
Purity
≥ 98% (HPLC)
Molecular Formula
C14H17F2NO4
Molecular Weight
301.3
MDL Number
MFCD00672518
PubChem ID
2756792
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-3,4-difluoro-L-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of novel therapeutic agents. Its unique fluorinated structure can enhance the stability and bioactivity of peptides.
  • Drug Development: Researchers leverage its properties to design and optimize drugs targeting specific biological pathways. The difluorophenyl group can improve binding affinity to certain receptors, making it a candidate for pharmaceuticals.
  • Bioconjugation: The compound is used in bioconjugation processes, where it can be attached to biomolecules for targeted drug delivery systems, enhancing the efficacy of treatments while minimizing side effects.
  • Fluorine Chemistry: Its incorporation into compounds allows for the exploration of fluorine's effects on biological activity, which is crucial in medicinal chemistry for developing more effective drugs.
  • Research in Neuropharmacology: The compound is investigated for its potential applications in neuropharmacology, particularly in the study of neurotransmitter systems, offering insights into treating neurological disorders.

Citations